PDB entry 4d2r

View 4d2r on RCSB PDB site
Description: Human IGF in complex with a Dyrk1B inhibitor
Class: transferase
Keywords: transferase, kinase, inhibitor, oncology
Deposited on 2014-05-12, released 2015-04-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2015-04-22, with a file datestamp of 2015-04-17.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4d2ra_
  • Heterogens: CL, DYK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4d2rA (A:)
dvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrer
ieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvl
appslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetd
yyrkggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrf
vmegglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyysee
nk

    Sequence, based on observed residues (ATOM records): (download) 
    >4d2rA (A:)
dvyvpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrer
ieflneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvl
appslskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetd
yyrkkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvm
egglldkpdncpdmlfelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk