PDB entry 4cwr

View 4cwr on RCSB PDB site
Description: Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor
Class: chaperone
Keywords: chaperone
Deposited on 2014-04-03, released 2014-07-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-08-06, with a file datestamp of 2014-08-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.18909
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4cwra_
  • Heterogens: HAJ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cwrA (A:)
gpdqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltd
pskldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqaga
dismigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkv
ilhlkedqteyleerrikeivkkhsqfigypitlfvekerdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >4cwrA (A:)
vetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgkel
hinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfgv
gfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqte
yleerrikeivkkhsqfigypitlfve