PDB entry 4cre
View 4cre on RCSB PDB site
Description: Creating novel F1 inhibitors through fragment based lead generation and structure aided drug design
Class: hydrolase
Keywords: hydrolase
Deposited on
2014-02-26, released
2015-02-11
The last revision prior to the SCOPe 2.06 freeze date was dated
2015-02-11, with a file datestamp of
2015-02-06.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: 0.174
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Coagulation factor XI
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P03951 (0-237)
- engineered mutation (64)
- engineered mutation (67)
- engineered mutation (105)
- engineered mutation (112)
- conflict (118)
Domains in SCOPe 2.06: d4crea_ - Heterogens: MVN, SO4, HOH