PDB entry 4bo2

View 4bo2 on RCSB PDB site
Description: Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(1-ethylbenzimidazol-2- yl)-3-(2-methoxyphenyl)urea at 1.9A resolution
Class: oxidoreductase
Keywords: oxidoreductase, rossmann fold, fatty acid biosynthesis
Deposited on 2013-05-18, released 2013-09-18
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-11-27, with a file datestamp of 2013-11-22.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.23671
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (18-21)
    Domains in SCOPe 2.06: d4bo2a1, d4bo2a2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4bo2b_
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (18-21)
    Domains in SCOPe 2.06: d4bo2c1, d4bo2c2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (17-21)
    Domains in SCOPe 2.06: d4bo2d1, d4bo2d2
  • Heterogens: 36K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bo2A (A:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo2A (A:)
yfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangveg
aglvldvssdesvaatlehiqqhlgqplivvnnagewfdvvntnlnslyrlskavlrgmt
karwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfidt
dmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bo2B (B:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo2B (B:)
slqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegaglvl
dvssdesvaatlehiqqhlgqplivvnnagidewfdvvntnlnslyrlskavlrgmtkar
wgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfidtdmt
relpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4bo2C (C:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo2C (C:)
yfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangveg
aglvldvssdesvaatlehiqqhlgqplivvnnagidewfdvvntnlnslyrlskavlrg
mtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfi
dtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4bo2D (D:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo2D (D:)
lyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangve
gaglvldvssdesvaatlehiqqhlgqplivvnnagirmkddewfdvvntnlnslyrlsk
avlrgmtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnav
apgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvng
gmyms