PDB entry 4bio
View 4bio on RCSB PDB site
Description: factor inhibiting hif-1 alpha in complex with 8-hydroxyquinoline-5- carboxylic acid
Class: oxidoreductase
Keywords: oxidoreductase, dioxygenase, oxygenase, DNA-binding, metal-binding, transcription, helix-loop-helix-beta, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, transcription and epigenetic regulation, signaling, development, cell structure, ankyrin repeat domain, ard, beta-hydroxylation, transcription activator/inhibitor, phosphorylation, s-nitrosylation
Deposited on
2013-04-12, released
2013-04-24
The last revision prior to the SCOPe 2.04 freeze date was dated
2014-02-05, with a file datestamp of
2014-01-31.
Experiment type: XRAY
Resolution: 2.45 Å
R-factor: 0.2009
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Hypoxia-inducible factor 1-alpha inhibitor
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d4bioa_ - Heterogens: FE, 8XQ, SO4, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4bioA (A:)
gshmaataaeavasgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelie
neepvvltdtnlvypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkpr
snreemkfhefveklqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkr
gwgqltsnllligmegnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcd
rqsqvdfdnpdyerfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwy
kgaptpkrieyplkahqkvaimrniekmlgealgnpqevgpllntmikgryn
Sequence, based on observed residues (ATOM records): (download)
>4bioA (A:)
sgsgepreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlv
ypalkwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefve
klqdiqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnlllig
megnvtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdye
rfpnfqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieypl
kahqkvaimrniekmlgealgnpqevgpllntmikgryn