PDB entry 4bd8

View 4bd8 on RCSB PDB site
Description: Bax domain swapped dimer induced by BimBH3 with CHAPS
Class: apoptosis
Keywords: apoptosis, programmed cell death
Deposited on 2012-10-05, released 2013-02-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-02-13, with a file datestamp of 2013-02-08.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: 0.2003
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Apoptosis regulator BAX
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07812
      • engineered mutation (61)
      • engineered mutation (125)
    Domains in SCOPe 2.08: d4bd8a_
  • Chain 'B':
    Compound: Apoptosis regulator BAX
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07812
      • engineered mutation (61)
      • engineered mutation (125)
    Domains in SCOPe 2.08: d4bd8b_
  • Chain 'C':
    Compound: Apoptosis regulator BAX
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07812
      • engineered mutation (61)
      • engineered mutation (125)
    Domains in SCOPe 2.08: d4bd8c_
  • Chain 'D':
    Compound: Apoptosis regulator BAX
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07812
      • engineered mutation (61)
      • engineered mutation (125)
    Domains in SCOPe 2.08: d4bd8d_
  • Heterogens: PR, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bd8A (A:)
mdgsgeqprgggptsseqimktgalllqgfiqdragrmggeapelaldpvpqdastkkls
eslkrigdeldsnmelqrmiaavdtdsprevffrvaadmfsdgnfnwgrvvalfyfaskl
vlkalstkvpelirtimgwtldflrerllgwiqdqggwdgllsyfgtptwqgss

    Sequence, based on observed residues (ATOM records): (download) 
    >4bd8A (A:)
ggptsseqimktgalllqgfiqdragrdastkklseslkrigdeldsnmelqrmiaavdt
dsprevffrvaadmfsdgnfnwgrvvalfyfasklvlkalstkvpelirtimgwtldflr
erllgwiqdqggwdgllsyfgtptw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bd8B (B:)
mdgsgeqprgggptsseqimktgalllqgfiqdragrmggeapelaldpvpqdastkkls
eslkrigdeldsnmelqrmiaavdtdsprevffrvaadmfsdgnfnwgrvvalfyfaskl
vlkalstkvpelirtimgwtldflrerllgwiqdqggwdgllsyfgtptwqgss

    Sequence, based on observed residues (ATOM records): (download) 
    >4bd8B (B:)
gptsseqimktgalllqgfiqdrapelaldpvpqdastkklseslkrigdeldsnmelqr
miaavdtdsprevffrvaadmfsdgnfnwgrvvalfyfasklvlkalstkvpelirtimg
wtldflrerllgwiqdqggwdgllsyfgtptw

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4bd8C (C:)
mdgsgeqprgggptsseqimktgalllqgfiqdragrmggeapelaldpvpqdastkkls
eslkrigdeldsnmelqrmiaavdtdsprevffrvaadmfsdgnfnwgrvvalfyfaskl
vlkalstkvpelirtimgwtldflrerllgwiqdqggwdgllsyfgtptwqgss

    Sequence, based on observed residues (ATOM records): (download) 
    >4bd8C (C:)
seqimktgalllqgfiqdragdastkklseslkrigdeldsnmelqrmiaprevffrvaa
dmfsdgnfnwgrvvalfyfasklvlkalstkvpelirtimgwtldflrerllgwiqdqgg
wdgllsyfgtptw

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4bd8D (D:)
mdgsgeqprgggptsseqimktgalllqgfiqdragrmggeapelaldpvpqdastkkls
eslkrigdeldsnmelqrmiaavdtdsprevffrvaadmfsdgnfnwgrvvalfyfaskl
vlkalstkvpelirtimgwtldflrerllgwiqdqggwdgllsyfgtptwqgss

    Sequence, based on observed residues (ATOM records): (download) 
    >4bd8D (D:)
tsseqimktgalllqgfiqdrapqdastkklseslkrigdeldsnmelqrmiaprevffr
vaadmfsdgnfnwgrvvalfyfasklvlkalstkvpelirtimgwtldflrerllgwiqd
qggwdgllsyfgtptw