PDB entry 4axx

View 4axx on RCSB PDB site
Description: THE CATALYTICALLY ACTIVE FULLY CLOSED CONFORMATION OF HUMAN PHOSPHOGLYCERATE KINASE IN COMPLEX WITH ADP 3-phosphoglycerate and beryllium trifluoride
Class: transferase
Keywords: ground state analogue, hereditary hemolytic anemia, phosphoprotein, glycolysis, transferase, phosphoryl transfer, nucleotide-binding
Deposited on 2012-06-15, released 2013-06-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-10-02, with a file datestamp of 2013-09-27.
Experiment type: XRAY
Resolution: 1.74 Å
R-factor: 0.17161
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoglycerate kinase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00558 (Start-416)
      • conflict (131)
    Domains in SCOPe 2.06: d4axxa_
  • Heterogens: MG, CL, ADP, 3PG, BEF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4axxA (A:)
mslsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvl
mshlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsville
nlrfhveeegkakdasgnkvkaepakieafraslsklgdvyvndafgtahrahssmvgvn
lpqkaggflmkkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggm
aftflkvlnnmeigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgq
atvasgipagwmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevv
katsrgcitiigggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni

    Sequence, based on observed residues (ATOM records): (download) 
    >4axxA (A:)
lsnkltldkldvkgkrvvmrvdfnvpmknnqitnnqrikaavpsikfcldngaksvvlms
hlgrpdgvpmpdkyslepvavelksllgkdvlflkdcvgpevekacanpaagsvillenl
rfhveeegkakaepakieafraslsklgdvyvndafgtahrahssmvgvnlpqkaggflm
kkelnyfakalesperpflailggakvadkiqlinnmldkvnemiigggmaftflkvlnn
meigtslfdeegakivkdlmskaekngvkitlpvdfvtadkfdenaktgqatvasgipag
wmgldcgpesskkyaeavtrakqivwngpvgvfeweafargtkalmdevvkatsrgciti
igggdtatccakwntedkvshvstgggaslellegkvlpgvdalsni