PDB entry 3znr

View 3znr on RCSB PDB site
Description: HDAC7 bound with inhibitor TMP269
Class: hydrolase
Keywords: hydrolase, class iia hdacs, tfmo
Deposited on 2013-02-15, released 2013-03-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-05-01, with a file datestamp of 2013-04-26.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.21385
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: histone deacetylase 7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3znra_
  • Chain 'B':
    Compound: histone deacetylase 7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3znrb_
  • Chain 'C':
    Compound: histone deacetylase 7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3znrc_
  • Heterogens: ZN, K, NU9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3znrA (A:)
gsraqsspaapaslsapepasqarvlsssetpartlpfttgliydsvmlkhqcscgdnsr
hpehagriqsiwsrlqerglrsqceclrgrkasleelqsvhserhvllygtnplsrlkld
ngklagllaqrmfvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkng
favvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyq
dpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafri
vvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlale
gghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmqr
las

    Sequence, based on observed residues (ATOM records): (download) 
    >3znrA (A:)
lpfttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasle
elqsvhserhvllygtnplsvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkva
srelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgng
tqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpe
ylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlagg
avvlalegghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhsk
ywgcmqrl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3znrB (B:)
gsraqsspaapaslsapepasqarvlsssetpartlpfttgliydsvmlkhqcscgdnsr
hpehagriqsiwsrlqerglrsqceclrgrkasleelqsvhserhvllygtnplsrlkld
ngklagllaqrmfvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkng
favvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyq
dpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafri
vvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlale
gghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmqr
las

    Sequence, based on observed residues (ATOM records): (download) 
    >3znrB (B:)
pfttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkaslee
lqsvhserhvllygtnplsrlkldngklagllaqvmlpcggvgvdtdtiwnelhssnaar
waagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqskas
kilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnvnv
awaggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsakc
fgymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkqkpnln
airsleavirvhskywgcmqr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3znrC (C:)
gsraqsspaapaslsapepasqarvlsssetpartlpfttgliydsvmlkhqcscgdnsr
hpehagriqsiwsrlqerglrsqceclrgrkasleelqsvhserhvllygtnplsrlkld
ngklagllaqrmfvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkng
favvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyq
dpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafri
vvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlale
gghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmqr
las

    Sequence, based on observed residues (ATOM records): (download) 
    >3znrC (C:)
ttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasleelq
svhserhvllygtnplpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkng
favvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyq
dpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafri
vvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlale
gghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmq