PDB entry 3vke

View 3vke on RCSB PDB site
Description: Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides
Class: DNA binding protein/DNA
Keywords: PCBP-1, DNA RNA BINDING PROTEIN, KH DOMAIN, DNA BINDING PROTEIN-DNA complex
Deposited on 2011-11-15, released 2012-02-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-07-17, with a file datestamp of 2013-07-12.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: 0.164
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Poly(rC)-binding protein 1
  Species: Homo sapiens [TaxId:9606]
  Gene: PCBP1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q15365 (2-74)
    • expression tag (0-1)
    • engineered mutation (42)
    • expression tag (75)
  Domains in SCOPe 2.06: d3vkea1, d3vkea2, d3vkea3
• Chain 'B':
  Compound: Poly(rC)-binding protein 1
  Species: Homo sapiens [TaxId:9606]
  Gene: PCBP1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q15365 (2-74)
    • expression tag (1)
    • engineered mutation (42)
    • expression tag (75)
  Domains in SCOPe 2.06: d3vkeb1, d3vkeb2, d3vkeb3
• Chain 'C':
  Compound: Poly(rC)-binding protein 1
  Species: Homo sapiens [TaxId:9606]
  Gene: PCBP1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q15365 (2-End)
    • expression tag (1)
    • engineered mutation (42)
  Domains in SCOPe 2.06: d3vkec1, d3vkec2
• Chain 'D':
  Compound: Poly(rC)-binding protein 1
  Species: Homo sapiens [TaxId:9606]
  Gene: PCBP1
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q15365 (2-End)
    • expression tag (1)
    • engineered mutation (42)
  Domains in SCOPe 2.06: d3vked1, d3vked2
• Chain 'R':
  Compound: DNA (5'-d(p*ap*cp*cp*cp*cp*a)-3')
  
• Chain 'S':
  Compound: DNA (5'-d(p*ap*cp*cp*cp*cp*a)-3')
  
• Chain 'T':
  Compound: DNA (5'-d(p*ap*cp*cp*cp*cp*a)-3')
  
• Chain 'U':
  Compound: DNA (5'-d(p*ap*cp*cp*cp*cp*a)-3')
  
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3vkeA (A:)
  hmltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifka
  famiidkleedinssw
  

  
  
• Chain 'B':
  Sequence, based on SEQRES records: (download)
  

  >3vkeB (B:)
  hmltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifka
  famiidkleedinssw
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3vkeB (B:)
  mltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifkaf
  amiidkleedinssw
  

  
  
• Chain 'C':
  Sequence, based on SEQRES records: (download)
  

  >3vkeC (C:)
  hmltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifka
  famiidkleedinssw
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3vkeC (C:)
  mltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifkaf
  amiidkleed
  

  
  
• Chain 'D':
  Sequence, based on SEQRES records: (download)
  

  >3vkeD (D:)
  hmltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifka
  famiidkleedinssw
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3vkeD (D:)
  mltirllmhgkevgsiigkkgesvkrireesgarinisegnsperiitltgptnaifkaf
  amiidkleedin
  

  
  
• Chain 'R':
  No sequence available.
  
  
• Chain 'S':
  No sequence available.
  
  
• Chain 'T':
  No sequence available.
  
  
• Chain 'U':
  No sequence available.