PDB entry 3v96

View 3v96 on RCSB PDB site
Description: Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-1 (TIMP-1)
Class: hydrolase inhibitor/hydrolase
Keywords: Metzincin, OB-fold, Metalloproteinase, Protease inhibitor, HYDROLASE INHIBITOR-HYDROLASE complex
Deposited on 2011-12-23, released 2012-03-28
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-07-25, with a file datestamp of 2012-07-20.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.218
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metalloproteinase inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLGI, TIMP, TIMP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3v96a_
  • Chain 'B':
    Compound: Stromelysin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP10, STMY2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3v96b_
  • Heterogens: PO4, ZN, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3v96A (A:)
ctcvpphpqtafcnsdlvirakfvgtpevaqttlyqryeikmtkmykgfqalgdaadirf
vytpamesvcgyfhrshnrseefliagklqdgllhittcsfvapwnslslaqrrgftkty
tvgceectvfpclsipcklqsgthclwtdqllqgsekgfqsrhlaclprepglctwqslr
sqia

    Sequence, based on observed residues (ATOM records): (download) 
    >3v96A (A:)
ctcvpphpqtafcnsdlvirakfvqttlyqryeikmtkmykgfirfvytpamesvcgyfh
rshnrseefliagklqdgllhittcsfvapwnslslaqrrgftktytvgceectvfpcls
ipcklqsgthclwtdqllqgsekgfqsrhlaclprepglctwqs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3v96B (B:)
fssfpgmpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadi
misfavkehgdfysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahe
lghslglfhsantealmyplynsftelaqfrlsqddvngiqslyg

    Sequence, based on observed residues (ATOM records): (download) 
    >3v96B (B:)
mpkwrkthltyrivnytpdlprdavdsaiekalkvweevtpltfsrlyegeadimisfav
kehgdfysfdgpghslahayppgpglygdihfdddekwtedasgtnlflvaahelghslg
lfhsantealmyplynsftelaqfrlsqddvngiqslyg