PDB entry 3upf

View 3upf on RCSB PDB site
Description: Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023
Class: transferase/transferase inhibitor
Keywords: murine norovirus, RNA-dependent RNA polymerase, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-11-18, released 2012-05-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-05-23, with a file datestamp of 2012-05-18.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.202
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-dependent RNA polymerase
    Species: Murine norovirus 1 [TaxId:223997]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3upfa_
  • Chain 'B':
    Compound: RNA-dependent RNA polymerase
    Species: Murine norovirus 1 [TaxId:223997]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3upfb_
  • Chain 'C':
    Compound: RNA-dependent RNA polymerase
    Species: Murine norovirus 1 [TaxId:223997]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3upfc_
  • Heterogens: 0BU, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3upfA (A:)
mkalefqgppmlprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgsk
dervdgpslqqvmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkac
esldkntssgypyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelv
kpdkiygkikkrllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifa
rhanfryhmdadytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdy
kivveeglpsgcpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstn
leldmvkytmalrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldras
idrqllwtkgpnhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsg
iemvvprhrsvlrwvrfgtmdaetpqersavfvnedelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3upfA (A:)
lprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqq
vmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgy
pyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikk
rllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmda
dytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsc
pcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytmal
rrygllptradkeeplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgpnh
qnpfetlpghrpqlmallgeaamhgekyyrtvasrvskeaavvprhrsvlrwvrfg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3upfB (B:)
mkalefqgppmlprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgsk
dervdgpslqqvmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkac
esldkntssgypyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelv
kpdkiygkikkrllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifa
rhanfryhmdadytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdy
kivveeglpsgcpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstn
leldmvkytmalrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldras
idrqllwtkgpnhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsg
iemvvprhrsvlrwvrfgtmdaetpqersavfvnedelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3upfB (B:)
lprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqq
vmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgy
pyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikk
rllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmda
dytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsg
ccttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytmal
rrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgpn
hqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsgvvprhrsvlrwv
rfg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3upfC (C:)
mkalefqgppmlprpsgtyaglpiadygdapplstktmfwrtspeklppgawepaylgsk
dervdgpslqqvmrdqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkac
esldkntssgypyhkqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelv
kpdkiygkikkrllwgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifa
rhanfryhmdadytrwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdy
kivveeglpsgcpcttqlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstn
leldmvkytmalrrygllptradkeegplerrqtlqgisflrraivgdqfgwygrldras
idrqllwtkgpnhqnpfetlpghaqrpsqlmallgeaamhgekyyrtvasrvskeaaqsg
iemvvprhrsvlrwvrfgtmdaetpqersavfvnedelehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3upfC (C:)
psgtyaglpiadygdapplstktmfwrtspeklppgawepaylgskdervdgpslqqvmr
dqlkpyseprgllppqeildavcdaienrlentlepqkpwtfkkacesldkntssgypyh
kqkskdwtgsafigdlgdqathannmyemgksmrpiytaalkdelvkpdkiygkikkrll
wgsdlgtmiraarafgpfcdalketcifnpirvgmsmnedgpfifarhanfryhmdadyt
rwdstqqrailkragdimvrlspepdlarvvmddllapslldvgdykivveeglpsgctt
qlnslahwiltlcamvevtrvdpdivmqesefsfygddevvstnleldmvkytmalrryg
llptradkeegplerrqtlqgisflrraivgdqfgwygrldrasidrqllwtkgpnhqnp
fetlpgqrpsqlmallgeaamhgekyyrtvasrvskevprhrsvlrwvrfg