PDB entry 3uas

View 3uas on RCSB PDB site
Description: Cytochrome P450 2B4 covalently bound to the mechanism-based inactivator 9-ethynylphenanthrene
Class: oxidoreductase
Keywords: P450, cytochrome P450 2B4, monooxygenase, oxidoreductase, membrane protein, CYP 2B4, CYP LM2
Deposited on 2011-10-21, released 2013-01-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 2.94 Å
R-factor: 0.245
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 2B4
    Species: Oryctolagus cuniculus [TaxId:9986]
    Gene: CYP2B4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00178 (Start-471)
      • engineered mutation (9)
      • see remark 999 (201)
      • engineered mutation (206)
      • expression tag (472)
    Domains in SCOPe 2.07: d3uasa1, d3uasa2
  • Heterogens: HEM, 0BV, TAM, CM5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3uasA (A:)
makktsskgklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlc
gtdairealvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgk
rsveeriqeearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrll
dlffqsfslissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldps
nprdfidvyllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyph
vtervqkeieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrg
yvipkntevfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclge
giartelflffttilqnfsiaspvppedidltpresgvgnvppsyqirflarhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3uasA (A:)
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdkrsveeriqeear
clveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfsliss
fssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidvyllr
mekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqkeieqv
igshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevfpv
lssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelflfft
tilqnfsiaspvppedidltpresgvgnvppsyqirflarh