PDB entry 3u15

View 3u15 on RCSB PDB site
Description: Structure of hDMX with Dimer Inducing Indolyl Hydantoin RO-2443
Class: protein binding
Keywords: cell cycle, ubiquitin ligase, MDM2, MDMX, p53, PROTEIN BINDING
Deposited on 2011-09-29, released 2012-06-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-11-08, with a file datestamp of 2017-11-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein Mdm4
    Species: Homo sapiens [TaxId:9606]
    Gene: mdm4, mdmx
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3u15a_
  • Chain 'B':
    Compound: Protein Mdm4
    Species: Homo sapiens [TaxId:9606]
    Gene: mdm4, mdmx
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3u15b_
  • Chain 'C':
    Compound: Protein Mdm4
    Species: Homo sapiens [TaxId:9606]
    Gene: mdm4, mdmx
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3u15c_
  • Chain 'D':
    Compound: Protein Mdm4
    Species: Homo sapiens [TaxId:9606]
    Gene: mdm4, mdmx
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3u15d_
  • Heterogens: 03M, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3u15A (A:)
gpdsasrispgqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeq
hmvycggdllgellgrqsfsvkdpsplydmlrknlvtlat

    Sequence, based on observed residues (ATOM records): (download) 
    >3u15A (A:)
qvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdllgell
grqsfsvkdpsplydmlrknlv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3u15B (B:)
gpdsasrispgqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeq
hmvycggdllgellgrqsfsvkdpsplydmlrknlvtlat

    Sequence, based on observed residues (ATOM records): (download) 
    >3u15B (B:)
qvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdllgell
grqsfsvkdpsplydmlrknlv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3u15C (C:)
gpdsasrispgqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeq
hmvycggdllgellgrqsfsvkdpsplydmlrknlvtlat

    Sequence, based on observed residues (ATOM records): (download) 
    >3u15C (C:)
qvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdllgell
grqsfsvkdpsplydmlrknlv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3u15D (D:)
gpdsasrispgqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeq
hmvycggdllgellgrqsfsvkdpsplydmlrknlvtlat

    Sequence, based on observed residues (ATOM records): (download) 
    >3u15D (D:)
qvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdllgell
grqsfsvkdpsplydmlrknl