PDB entry 3tww

View 3tww on RCSB PDB site
Description: Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human LNPEP (chimeric peptide)
Class: signaling protein/peptide
Keywords: ankyrin repeat, protein-protein interaction, substrate recruitment, poly(ADP-ribosyl)ation, SIGNALING PROTEIN-PEPTIDE complex
Deposited on 2011-09-22, released 2011-12-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-12-28, with a file datestamp of 2011-12-23.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.221
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP5B, TANK2, TNKL, TNKS2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3twwa_
  • Chain 'B':
    Compound: tankyrase-2
    Species: Homo sapiens [TaxId:9606]
    Gene: PARP5B, TANK2, TNKL, TNKS2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H2K2 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.07: d3twwb1, d3twwb2
  • Chain 'C':
    Compound: human LNPEP
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TWW (Start-15)
  • Chain 'D':
    Compound: human LNPEP
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 3TWW (Start-15)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3twwA (A:)
gamgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvvey
llqhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgk
yeicklllqhgadptkknrdgntpldlvkdgdtdiqdllrgdaal

    Sequence, based on observed residues (ATOM records): (download) 
    >3twwA (A:)
gnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvveyllq
hgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgkyei
cklllqhgadptkknrdgntpldlvkdgdtdiqdllr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3twwB (B:)
gamgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvvey
llqhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgk
yeicklllqhgadptkknrdgntpldlvkdgdtdiqdllrgdaal

    Sequence, based on observed residues (ATOM records): (download) 
    >3twwB (B:)
mgnseadrqlleaakagdvetvkklctvqsvncrdiegrqstplhfaagynrvsvveyll
qhgadvhakdkgglvplhnacsyghyevaellvkhgavvnvadlwkftplheaaakgkye
icklllqhgadptkknrdgntpldlvkdgdtdiqdll

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.