SCOPe 2.07: Structural Classification of Proteins

PDB entry 3tkr

View 3tkr on RCSB PDB site
Description: Crystal structure of full-length human peroxiredoxin 4 with T118E mutation
Class: oxidoreductase
Keywords: Trx fold, peroxiredoxin, OXIDOREDUCTASE
Deposited on 2011-08-28, released 2011-10-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-10-05, with a file datestamp of 2011-09-30.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.152
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkra_
Chain 'B':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrb_
Chain 'C':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrc_
Chain 'D':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrd_
Chain 'E':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkre_
Chain 'F':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrf_
Chain 'G':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrg_
Chain 'H':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrh_
Chain 'I':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkri_
Chain 'J':
Compound: Peroxiredoxin-4
Species: Homo sapiens [TaxId:9606]
Gene: PRDX4
Database cross-references and differences (RAF-indexed):
- Uniprot Q13162 (Start-245)
  - engineered mutation (129)
Domains in SCOPe 2.07: d3tkrj_
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3tkrA (A:)
mrgshhhhhhgsweteerprtreeechfyaggqvypgeasrvsvadhslhlskakiskpa
pywegtavidgefkelkltdyrgkylvfffypldftfvcpteiiafgdrleefrsintev
vacsvdsqfehlawintprrqgglgpiripllsdlthqiskdygvyledsghtlrglfii
ddkgilrqitlndlpvgrsvdetlrlvqafqytdkhgevcpagwkpgsetiipdpagklk
yfdkln