PDB entry 3tdb

View 3tdb on RCSB PDB site
Description: Human Pin1 bound to trans peptidomimetic inhibitor
Class: ISOMERASE/Inhibitor
Keywords: PPIase domain, WW domain, Peptidyl-prolyl isomerase, ISOMERASE-Inhibitor complex
Deposited on 2011-08-10, released 2012-06-27
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-09-05, with a file datestamp of 2012-08-31.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: 0.221
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13526 (0-157)
      • engineered mutation (8)
    Domains in SCOPe 2.04: d3tdba1, d3tdba2
  • Heterogens: 3TB, PE4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3tdbA (A:)
klppgwekamsrssgrvyyfnhitnasqwerpsgnsssggkngqgeparvrcshllvkhs
qsrrpsswrqekitrtkeealelingyiqkiksgeedfeslasqfsdcssakargdlgaf
srgqmqkpfedasfalrtgemsgpvftdsgihiilrte

    Sequence, based on observed residues (ATOM records): (download) 
    >3tdbA (A:)
klppgwekamsrssgrvyyfnhitnasqwerpseparvrcshllvkhsqsrrpsswrqek
itrtkeealelingyiqkiksgeedfeslasqfsdcssakargdlgafsrgqmqkpfeda
sfalrtgemsgpvftdsgihiilrte