PDB entry 3t80

View 3t80 on RCSB PDB site
Description: Crystal structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Salmonella typhimurium bound to cytidine
Class: lyase
Keywords: IspF, Isoprenoid biosynthesis, SSGCID, Structural Genomics, Seattle Structural Genomics Center for Infectious Disease, Alpha Beta, LYASE
Deposited on 2011-07-31, released 2011-09-14
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-10-12, with a file datestamp of 2011-10-07.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.212
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:90371]
    Gene: ispF, STM2929
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZMF7 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.04: d3t80a_
  • Chain 'B':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:90371]
    Gene: ispF, STM2929
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZMF7 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.04: d3t80b_
  • Chain 'C':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:90371]
    Gene: ispF, STM2929
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZMF7 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.04: d3t80c_
  • Chain 'D':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:90371]
    Gene: ispF, STM2929
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZMF7 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.04: d3t80d_
  • Chain 'E':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:90371]
    Gene: ispF, STM2929
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZMF7 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.04: d3t80e_
  • Chain 'F':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Salmonella enterica subsp. enterica serovar Typhimurium [TaxId:90371]
    Gene: ispF, STM2929
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8ZMF7 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.04: d3t80f_
  • Heterogens: ZN, MG, CTN, POP, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3t80A (A:)
snamrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdi
gklfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfia
edlgchmdevnvkattteklgftgrgegiaceavallmkaak

    Sequence, based on observed residues (ATOM records): (download) 
    >3t80A (A:)
amrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdigk
lfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiaed
lgchmdevnvkattteklgftgrgegiaceavallmk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3t80B (B:)
snamrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdi
gklfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfia
edlgchmdevnvkattteklgftgrgegiaceavallmkaak

    Sequence, based on observed residues (ATOM records): (download) 
    >3t80B (B:)
amrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdigk
ladsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiaedlgchmdevnv
kattteklgftgrgegiaceavallmk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3t80C (C:)
snamrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdi
gklfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfia
edlgchmdevnvkattteklgftgrgegiaceavallmkaak

    Sequence, based on observed residues (ATOM records): (download) 
    >3t80C (C:)
amrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdigk
lfpdgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiaedlgchmd
evnvkattteklgftgrgegiaceavallmk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3t80D (D:)
snamrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdi
gklfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfia
edlgchmdevnvkattteklgftgrgegiaceavallmkaak

    Sequence, based on observed residues (ATOM records): (download) 
    >3t80D (D:)
amrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdigk
lfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiaed
lgchmdevnvkattteklgftgrgegiaceavallmk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3t80E (E:)
snamrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdi
gklfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfia
edlgchmdevnvkattteklgftgrgegiaceavallmkaak

    Sequence, based on observed residues (ATOM records): (download) 
    >3t80E (E:)
amrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdigk
lfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiaed
lgchmdevnvkattteklgftgrgegiaceavallmk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3t80F (F:)
snamrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdi
gklfpdtdpafkgadsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfia
edlgchmdevnvkattteklgftgrgegiaceavallmkaak

    Sequence, based on observed residues (ATOM records): (download) 
    >3t80F (F:)
amrighgfdvhafggegpiiiggvripyekgllahsdgdvalhaltdallgaaalgdigk
ldsrellreawrriqakgytlgnvdvtiiaqapkmlphipqmrvfiaedlgchmdevnvk
attteklgftgrgegiaceavallmk