PDB entry 3sq3

View 3sq3 on RCSB PDB site
Description: Crystal Structure Analysis of the Yeast Tyrosyl-DNA Phosphodiesterase H182A Mutant
Class: hydrolase
Keywords: Phosphodiesterase, DNA Binding, NUCLEAR, HYDROLASE
Deposited on 2011-07-04, released 2011-12-28
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-03-14, with a file datestamp of 2012-03-09.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.206
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: tyrosyl-DNA phosphodiesterase 1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: TDP1, YBR223C, YBR1520
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38319 (1-461)
      • engineered mutation (104)
      • expression tag (462)
    Domains in SCOPe 2.03: d3sq3a1, d3sq3a2
  • Chain 'B':
    Compound: tyrosyl-DNA phosphodiesterase 1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: TDP1, YBR223C, YBR1520
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38319 (1-461)
      • engineered mutation (104)
  • Chain 'C':
    Compound: tyrosyl-DNA phosphodiesterase 1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: TDP1, YBR223C, YBR1520
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38319 (1-End)
      • engineered mutation (104)
  • Chain 'D':
    Compound: tyrosyl-DNA phosphodiesterase 1
    Species: Saccharomyces cerevisiae [TaxId:559292]
    Gene: TDP1, YBR223C, YBR1520
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38319 (1-461)
      • engineered mutation (104)
      • expression tag (462)

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sq3A (A:)
mgavfklmksdfyeredfmgevedmitlkdifgtetlkrsilfsfqyeldfllrqfhqnv
enitivgqkgtimpiearamdatlavilkkvklieitmppfashatkliinfydngecki
flpsnnftsmetnlpqqvcwcspllkigkeglpvpfkrslieylnsyhlkdidelitksv
eevnfaplselefvystpskfqssgllsfynkleklsagtsasdtakhylcqtssigtsl
srardenlwthlmiplftgimsppakdtagrkkaeilptnslineysqrkikpyiifpte
qefvtsplkwsssgwfhfqylqkksyyemlrnkfkvfykqdpamvtrrrgttpahskfym
hcatnsagpcdasqvfkelewclytsanlsqtawgtvsrkprnyeagvlyhsrrlantrk
vtcrtftrdrrgcagnpthvavpftlpvipydlaedecfclalhhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3sq3A (A:)
gavfklmksdfyeredmitlkdifgtetlkrsilfsfqyeldfllrqfhqnvenitivgq
kgtimpiearamdatlavilkkvklieitmppfashatkliinfydngeckiflpsnnft
smetnlpqqvcwcspllkigkeglpvpfkrslieylnsyhlkdidelitksveevnfapl
selefvystpskfqssgllsfynkleklsdtakhylcqtssigtslsrardenlwthlmi
plftgimsppilptnslineysqrkikpyiifpteqefvtsplkwsssgwfhfqylqkks
yyemlrnkfkvfykqdpamvtrrrgttpahskfymhcatnsqvfkelewclytsanlsqt
awgtvsrkprnyeagvlyhsrrlantrkvtcrtftrdpthvavpftlpvipydlaedecf
clal

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.