PDB entry 3sir

View 3sir on RCSB PDB site
Description: Crystal Structure of drICE
Class: hydrolase
Keywords: caspase, HYDROLASE
Deposited on 2011-06-20, released 2011-08-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-07-25, with a file datestamp of 2018-07-20.
Experiment type: XRAY
Resolution: 2.68 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Caspase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O01382 (4-End)
      • see remark 999 (0-3)
      • engineered mutation (77)
    Domains in SCOPe 2.08: d3sira_
  • Chain 'B':
    Compound: Caspase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O01382
      • engineered mutation (77)
    Domains in SCOPe 2.08: d3sirb_
  • Chain 'C':
    Compound: Caspase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O01382
      • engineered mutation (77)
    Domains in SCOPe 2.08: d3sirc_
  • Chain 'D':
    Compound: Caspase
    Species: Drosophila melanogaster [TaxId:7227]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O01382 (Start-258)
      • engineered mutation (77)
    Domains in SCOPe 2.08: d3sird_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sirA (A:)
algsvtdrhaaeynmrhknrgmalifnhehfevptlksragtnvdcenltrvlkqldfev
tvykdcrykdilrtieysasqnhsdsdcilvailshgemgyiyakdtqykldniwsffta
nhcpslagkpklffiqacqgdrldggvtmqrsqtetdgdssmsykipvhadfliaystvp
gfyswrnttrgswfmqslcaelaangkrldiltlltfvcqrvavdfesctpdtpemhqqk
qipcittmltrilrfsdkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3sirA (A:)
algsvtdrhaaeynmrhknrgmalifnhehfnvdcenltrvlkqldfevtvykdcrykdi
lrtieysasqnhsdsdcilvailshgemgyiyakdtqykldniwsfftanhcpslagkpk
lffiqacqgdrldgsykipvhadfliaystvpgfyswrnttrgswfmqslcaelaangkr
ldiltlltfvcqrvavdfqipcittmltrilrfs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3sirB (B:)
algsvtdrhaaeynmrhknrgmalifnhehfevptlksragtnvdcenltrvlkqldfev
tvykdcrykdilrtieysasqnhsdsdcilvailshgemgyiyakdtqykldniwsffta
nhcpslagkpklffiqacqgdrldggvtmqrsqtetdgdssmsykipvhadfliaystvp
gfyswrnttrgswfmqslcaelaangkrldiltlltfvcqrvavdfesctpdtpemhqqk
qipcittmltrilrfsdkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3sirB (B:)
aaeynmrhknrgmalifnnvdcenltrvlkqldfevtvykdcrykdilrtieysasqnhs
dsdcilvailshiwsfftanhcpslagkpklffiqacsykipvhadfliaystvptrgsw
fmqslcaelaangkrldiltlltfvcqrvavdfescqipcittmltrilrfs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3sirC (C:)
algsvtdrhaaeynmrhknrgmalifnhehfevptlksragtnvdcenltrvlkqldfev
tvykdcrykdilrtieysasqnhsdsdcilvailshgemgyiyakdtqykldniwsffta
nhcpslagkpklffiqacqgdrldggvtmqrsqtetdgdssmsykipvhadfliaystvp
gfyswrnttrgswfmqslcaelaangkrldiltlltfvcqrvavdfesctpdtpemhqqk
qipcittmltrilrfsdkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3sirC (C:)
aaeynmrhknrgmalifnhnvdcenltrvlkqldfevtvykdcrykdilrtieysasqnh
sdsdcilvailsniwsfftanhcpslagkpklffiqacqvhadfliaystvpswfmqslc
aelaangkrldiltlltfvcqrvavdqipcittmltrilrfs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3sirD (D:)
algsvtdrhaaeynmrhknrgmalifnhehfevptlksragtnvdcenltrvlkqldfev
tvykdcrykdilrtieysasqnhsdsdcilvailshgemgyiyakdtqykldniwsffta
nhcpslagkpklffiqacqgdrldggvtmqrsqtetdgdssmsykipvhadfliaystvp
gfyswrnttrgswfmqslcaelaangkrldiltlltfvcqrvavdfesctpdtpemhqqk
qipcittmltrilrfsdkq

    Sequence, based on observed residues (ATOM records): (download) 
    >3sirD (D:)
aaeynmrhknrgmalifnhnvdcenltrvlkqldfevtvykdkdilrtieysasqnhsds
dcilvailsiwsfftanhcpslagkpklffiqaadfliaystvpgfyswrnttrgswfmq
slcaelaangkrldiltlltfvcqrvavdfqipcittmltrilrfsdkq