PDB entry 3sf8

View 3sf8 on RCSB PDB site
Description: Structural insights into thiol stabilization of DJ-1
Class: oncoprotein,unknown function
Keywords: oxidative stress, redox regulation, cysteine oxidation, protecting DJ-1 oxidation, reduced DJ-1, class I glutamine amidotransferase family, cytoprotective activity against oxidative stress; Cysteine sulfenic acid modification, HYDROLASE, ONCOPROTEIN,UNKNOWN FUNCTION
Deposited on 2011-06-13, released 2011-10-05
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-11-23, with a file datestamp of 2011-11-18.
Experiment type: XRAY
Resolution: 1.56 Å
R-factor: 0.174
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein DJ-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARK7
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99497 (Start-188)
      • expression tag (189-190)
    Domains in SCOPe 2.02: d3sf8a_
  • Chain 'B':
    Compound: Protein DJ-1
    Species: Homo sapiens [TaxId:9606]
    Gene: PARK7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3sf8b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3sf8A (A:)
maskralvilakgaeemetvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasled
akkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfg
skvtthplakdkmmngghytysenrvekdgliltsrgpgtsfefalaivealngkevaaq
vkaplvlkdle

    Sequence, based on observed residues (ATOM records): (download) 
    >3sf8A (A:)
askralvilakgaeemetvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasleda
kkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfgs
kvtthplakdkmmngghytysenrvekdgliltsrgpgtsfefalaivealngkevaaqv
kaplvlkdle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3sf8B (B:)
maskralvilakgaeemetvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasled
akkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfg
skvtthplakdkmmngghytysenrvekdgliltsrgpgtsfefalaivealngkevaaq
vkaplvlkdle

    Sequence, based on observed residues (ATOM records): (download) 
    >3sf8B (B:)
askralvilakgaeemetvipvdvmrragikvtvaglagkdpvqcsrdvvicpdasleda
kkegpydvvvlpggnlgaqnlsesaavkeilkeqenrkgliaaicagptallaheigfgs
kvtthplakdkmmngghytysenrvekdgliltsrgpgtsfefalaivealngkevaaqv
kaplvlk