PDB entry 3s9k

View 3s9k on RCSB PDB site
Description: Crystal structure of the Itk SH2 domain.
Class: transferase
Keywords: proline isomerization, cis proline, domain swapped dimer, SH2 domain, TRANSFERASE
Deposited on 2011-06-01, released 2012-02-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-15, with a file datestamp of 2012-02-10.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.237
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase ITK/TSK
    Species: Mus musculus [TaxId:10090]
    Gene: Emt, IL-2 inducible T cell kinase, Itk, Tlk, Tsk
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q03526 (Start-109)
      • expression tag (110-117)
    Domains in SCOPe 2.08: d3s9ka1, d3s9ka2
  • Heterogens: CIT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3s9kA (A:)
gspnnletyewynksisrdkaekllldtgkegafmvrdsrtpgtytvsvftkaiisenpc
ikhyhiketndspkryyvaekyvfdsiplliqyhqynggglvtrlrypvcgspgihrd

    Sequence, based on observed residues (ATOM records): (download) 
    >3s9kA (A:)
nletyewynksisrdkaekllldtgkegafmvrdsrtpgtytvsvftkaiisenpcikhy
hiketndspkryyvaekyvfdsiplliqyhqynggglvtrlrypvcgspgihrd