PDB entry 3s3g

View 3s3g on RCSB PDB site
Description: Crystal Structure of Human Aldose Reductase Complexed with Tolmetin
Class: oxidoreductase
Keywords: Human Aldose Reductase, OXIDOREDUCTASE
Deposited on 2011-05-18, released 2012-04-04
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-04-04, with a file datestamp of 2012-03-30.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.163
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: aldose reductase
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1B1, ALDR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3s3ga_
  • Heterogens: NAP, TLT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3s3gA (A:)
mgsshhhhhhssglvprgshmasrlllnngakmpilglgtwksppgqvteavkvaidvgy
rhidcahvyqnenevgvaiqeklreqvvkreelfivsklwctyhekglvkgacqktlsdl
kldyldlylihwptgfkpgkeffpldesgnvvpsdtnildtwaameelvdeglvkaigis
nfnhlqvemilnkpglkykpavnqiechpyltqekliqycqskgivvtaysplgspdrpw
akpedpslledprikaiaakhnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfe
lssqdmttllsynrnwrvcallsctshkdypfheef

    Sequence, based on observed residues (ATOM records): (download) 
    >3s3gA (A:)
masrlllnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef