PDB entry 3rq7

View 3rq7 on RCSB PDB site
Description: Polo-like kinase 1 Polo box domain in complex with a C6H5(CH2)8-derivatized peptide inhibitor
Class: transferase/transferase inhibitor
Keywords: phosphopeptide binding domain, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-04-27, released 2011-07-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-10-10, with a file datestamp of 2012-10-05.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.154
AEROSPACI score: 0.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK1, PLK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3rq7a1, d3rq7a2
  • Chain 'B':
    Compound: C6H5(CH2)8-derivatized peptide inhibitor
    Database cross-references and differences (RAF-indexed):
    • PDB 3RQ7
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rq7A (A:)
gahmdchlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyq
lcdnsvgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnym
sehllkaganitpregdelarlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcpl
maavtyidekrdfrtyrlslleeygcckelasrlryartmvdkllssrsasnrlkas

    Sequence, based on observed residues (ATOM records): (download) 
    >3rq7A (A:)
hlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdnsv
gvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehllk
agaprlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidekrdfrty
rlslleeygcckelasrlryartmvdkllssr

  • Chain 'B':
    No sequence available.