PDB entry 3ri4

View 3ri4 on RCSB PDB site
Description: Ets1 cooperative binding to widely separated sites on promoter DNA
Class: Transcription/DNA
Keywords: transcription, T-cell receptor alpha, DNA binding, autoinhibition, Ets domain, transcription factor, DNA, Runx2, Runx1, Transcription-DNA complex
Deposited on 2011-04-12, released 2012-04-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-12-16, with a file datestamp of 2015-12-11.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein C-ets-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ETS1, EWSR2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3ri4a_
  • Chain 'B':
    Compound: TCR alpha promoter DNA
  • Chain 'C':
    Compound: TCR alpha promoter DNA
  • Chain 'D':
    Compound: Protein C-ets-1
    Species: Homo sapiens [TaxId:9606]
    Gene: ETS1, EWSR2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3ri4d_
  • Chain 'E':
    Compound: TCR alpha promoter DNA
  • Chain 'F':
    Compound: TCR alpha promoter DNA
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ri4A (A:)
mvpsydsfdyedypaalpnhkpkgtfkdyvrdradlnkdkpvipaaalagytgsgpiqlw
qfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeklsrglryyyd
kniihktagkryvyrfvcdlqsllgytpeelhamldvkpdade

    Sequence, based on observed residues (ATOM records): (download) 
    >3ri4A (A:)
gtfkdyvrdradlnkdkpvipaaalagytgsgpiqlwqfllelltdkscqsfiswtgdgw
efklsdpdevarrwgkrknkpkmnyeklsrglryyydkniihktagkryvyrfvcdlqsl
lgytpeelhamldvkp

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3ri4D (D:)
mvpsydsfdyedypaalpnhkpkgtfkdyvrdradlnkdkpvipaaalagytgsgpiqlw
qfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyeklsrglryyyd
kniihktagkryvyrfvcdlqsllgytpeelhamldvkpdade

    Sequence, based on observed residues (ATOM records): (download) 
    >3ri4D (D:)
gtfkdyvrdradlnkdkpvipaaalagytgsgpiqlwqfllelltdkscqsfiswtgdgw
efklsdpdevarrwgkrknkpkmnyeklsrglryyydkniihktagkryvyrfvcdlqsl
lgytpeelhamldvkp

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.