PDB entry 3rcl

View 3rcl on RCSB PDB site
Description: Human Cyclophilin D Complexed with a Fragment
Class: isomerase/isomerase inhibitor
Keywords: beta barrel, prolyl cis/trans isomerase, mitochondria, inhibitor, ISOMERASE-ISOMERASE INHIBITOR complex
Deposited on 2011-03-31, released 2012-03-21
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-03-21, with a file datestamp of 2012-03-16.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.134
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase F, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: PPIF, CYP3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30405 (Start-165)
      • engineered mutation (133)
    Domains in SCOPe 2.06: d3rcla_
  • Heterogens: 5AO, P4C, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3rclA (A:)
msgnplvyldvdangkplgrvvlelkadvvpktaenfralctgekgfgykgstfhrvips
fmcqagdftnhngtggksiygsrfpdenftlkhvgpgvlsmanagpntngsqffictikt
dwldgkhvvfghviegmdvvkkiesfgsksgrtskkivitdcgqls

    Sequence, based on observed residues (ATOM records): (download) 
    >3rclA (A:)
gnplvyldvdangkplgrvvlelkadvvpktaenfralctgekgfgykgstfhrvipsfm
cqagdftnhngtggksiygsrfpdenftlkhvgpgvlsmanagpntngsqffictiktdw
ldgkhvvfghviegmdvvkkiesfgsksgrtskkivitdcgqls