PDB entry 3r9a

View 3r9a on RCSB PDB site
Description: Human alanine-glyoxylate aminotransferase in complex with the TPR domain of human PEX5P
Class: transferase/transport protein
Keywords: tpr-domain, protein-protein complex, peroxisome, aminotransf pyruvate, transferase, disease mutation, membrane, peroxiso biogenesis disorder, protein transport, tpr repeat, transpo zellweger syndrome, transferase-transport protein complex, mitochondrion, pyridoxal phosphate
Deposited on 2011-03-25, released 2011-05-11
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-05-02, with a file datestamp of 2012-04-27.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.187
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine--pyruvate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT1, AGXT, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3r9aa_
  • Chain 'B':
    Compound: peroxisomal targeting signal 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: PEX5, PXR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3r9ab_
  • Chain 'C':
    Compound: Serine--pyruvate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: AGT1, AGXT, SPAT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3r9ac_
  • Chain 'D':
    Compound: peroxisomal targeting signal 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: PEX5, PXR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3r9ad_
  • Heterogens: BTB, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3r9aA (A:)
gamashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimd
eikegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdiger
igarvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykc
lllvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpf
sfyldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaayl
hgrlqalglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkv
lrigllgcnatrenvdrvtealraalqhcpkkkl

    Sequence, based on observed residues (ATOM records): (download) 
    >3r9aA (A:)
llvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikegiq
yvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarvhp
mtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvdsv
aslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyldik
wlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlqal
glqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigllg
cnatrenvdrvtealraalqhcpkkkl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3r9aB (B:)
gamltsatydkgyqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmea
wqylgttqaeneqellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlr
ytpayahlvtpaeegaggaglgpskrilgsllsdslflevkelflaavrldptsidpdvq
cglgvlfnlsgeydkavdcftaalsvrpndyllwnklgatlangnqseeavaayrralel
qpgyirsrynlgiscinlgahreavehflealnmqrksrgprgeggamseniwstlrlal
smlgqsdaygaadardlstlltmfglpq

    Sequence, based on observed residues (ATOM records): (download) 
    >3r9aB (B:)
qfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmeawqylgttqaeneq
ellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlrytpayahlvdslf
levkelflaavrldptsidpdvqcglgvlfnlsgeydkavdcftaalsvrpndyllwnkl
gatlangnqseeavaayrralelqpgyirsrynlgiscinlgahreavehflealnmqrk
srrgeggamseniwstlrlalsmlgqsdaygaadardlstlltmfglpq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3r9aC (C:)
gamashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimd
eikegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdiger
igarvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykc
lllvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpf
sfyldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaayl
hgrlqalglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkv
lrigllgcnatrenvdrvtealraalqhcpkkkl

    Sequence, based on observed residues (ATOM records): (download) 
    >3r9aC (C:)
hkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikeg
iqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarv
hpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvd
svaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyld
ikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlq
alglqlfvkdpalrlptvttvavpagydwrdivsyvidhfdieimgglgpstgkvlrigl
lgcnatrenvdrvtealraalqhcpkkkl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3r9aD (D:)
gamltsatydkgyqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmea
wqylgttqaeneqellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlr
ytpayahlvtpaeegaggaglgpskrilgsllsdslflevkelflaavrldptsidpdvq
cglgvlfnlsgeydkavdcftaalsvrpndyllwnklgatlangnqseeavaayrralel
qpgyirsrynlgiscinlgahreavehflealnmqrksrgprgeggamseniwstlrlal
smlgqsdaygaadardlstlltmfglpq

    Sequence, based on observed residues (ATOM records): (download) 
    >3r9aD (D:)
yqfeeenplrdhpqpfeeglrrlqegdlpnavllfeaavqqdpkhmeawqylgttqaene
qellaisalrrclelkpdnqtalmalavsftneslqrqacetlrdwlrytpayahlvtpa
sllsdslflevkelflaavrldptsidpdvqcglgvlfnlsgeydkavdcftaalsvrpn
dyllwnklgatlangnqseeavaayrralelqpgyirsrynlgiscinlgahreavehfl
ealnmqrksgamseniwstlrlalsmlgqsdaygaadardlstlltmfglpq