PDB entry 3r0f

View 3r0f on RCSB PDB site
Description: Human enterovirus 71 3C protease mutant H133G in complex with rupintrivir
Class: hydrolase/hydrolase inhibitor
Keywords: chymotrypsin-fold, beta-ribbon, hydrolysis, nucleus, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-03-08, released 2011-08-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-05-06, with a file datestamp of 2015-05-01.
Experiment type: XRAY
Resolution: 1.31 Å
R-factor: N/A
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C protein
    Species: Human enterovirus 71 [TaxId:39054]
    Gene: polyprotein
    Database cross-references and differences (RAF-indexed):
    • Uniprot E7E815 (4-End)
      • engineered mutation (136)
    Domains in SCOPe 2.06: d3r0fa_
  • Chain 'B':
    Compound: 3C protein
    Species: Human enterovirus 71 [TaxId:39054]
    Gene: polyprotein
    Database cross-references and differences (RAF-indexed):
    • Uniprot E7E815
      • engineered mutation (136)
    Domains in SCOPe 2.06: d3r0fb_
  • Heterogens: AG7, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3r0fA (A:)
gshmgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnv
ldavelvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpv
gdvvqygflnlsgkptgrtmmynfptkagqcggvvtsvgkiigihiggngrqgfcaglkr
syfaseq

    Sequence, based on observed residues (ATOM records): (download) 
    >3r0fA (A:)
gpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnvldav
elvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdvv
qygflnlsgkptgrtmmynfptkagqcggvvtsvgkiigihiggngrqgfcaglkrsyfa
s

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3r0fB (B:)
gshmgpsldfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnv
ldavelvdeqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpv
gdvvqygflnlsgkptgrtmmynfptkagqcggvvtsvgkiigihiggngrqgfcaglkr
syfaseq

    Sequence, based on observed residues (ATOM records): (download) 
    >3r0fB (B:)
dfalsllrrnvrqvqtdqghftmlgvrdrlavlprhsqpgktiwiehklvnvldavelvd
eqgvnleltlitldtnekfrditkfipenistasdatlvintehmpsmfvpvgdvvqygf
lnlsgkptgrtmmynfptkagqcggvvtsvgkiigihiggngrqgfcaglkrsyfa