PDB entry 3qna

View 3qna on RCSB PDB site
Description: Crystal structure of a 6-pyruvoyltetrahydropterin synthase homologue from Esherichia coli complexed sepiapterin
Class: lyase
Keywords: 6-pyruvoyltetrahydropterin synthase, Bh4 synthase, Zn, sepaitperin, LYASE
Deposited on 2011-02-08, released 2011-12-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-05-28, with a file datestamp of 2014-05-23.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.184
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 6-carboxy-5,6,7,8-tetrahydropterin synthase
    Species: ESCHERICHIA COLI [TaxId:469008]
    Gene: EcDH1_0923
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6EJA7
      • engineered mutation (46)
    Domains in SCOPe 2.05: d3qnaa_
  • Chain 'B':
    Compound: 6-carboxy-5,6,7,8-tetrahydropterin synthase
    Species: ESCHERICHIA COLI [TaxId:469008]
    Gene: EcDH1_0923
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6EJA7
      • engineered mutation (46)
    Domains in SCOPe 2.05: d3qnab_
  • Chain 'C':
    Compound: 6-carboxy-5,6,7,8-tetrahydropterin synthase
    Species: ESCHERICHIA COLI [TaxId:469008]
    Gene: EcDH1_0923
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6EJA7
      • engineered mutation (46)
    Domains in SCOPe 2.05: d3qnac_
  • Chain 'D':
    Compound: 6-carboxy-5,6,7,8-tetrahydropterin synthase
    Species: ESCHERICHIA COLI [TaxId:469008]
    Gene: EcDH1_0923
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6EJA7
      • engineered mutation (46)
    Domains in SCOPe 2.05: d3qnad_
  • Chain 'E':
    Compound: 6-carboxy-5,6,7,8-tetrahydropterin synthase
    Species: ESCHERICHIA COLI [TaxId:469008]
    Gene: EcDH1_0923
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6EJA7
      • engineered mutation (46)
    Domains in SCOPe 2.05: d3qnae_
  • Chain 'F':
    Compound: 6-carboxy-5,6,7,8-tetrahydropterin synthase
    Species: ESCHERICHIA COLI [TaxId:469008]
    Gene: EcDH1_0923
    Database cross-references and differences (RAF-indexed):
    • Uniprot C6EJA7
      • engineered mutation (46)
    Domains in SCOPe 2.05: d3qnaf_
  • Heterogens: BIO, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qnaA (A:)
mgsshhhhhhssglvprgshmmsttlfkdftfeaahrlphvpeghkagrlhghsfmvrle
itgevdphtgwiidfaelkaafkptyerldhhylndipglenptsevlakwiwdqvkpvv
pllsavmvketctagciyrge

    Sequence, based on observed residues (ATOM records): (download) 
    >3qnaA (A:)
sttlfkdftfeaahrlphvpeghkagrlhghsfmvrleitgevdphtgwiidfaelkaaf
kptyerldhhylndipglenptsevlakwiwdqvkpvvpllsavmvketctagciyrg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qnaB (B:)
mgsshhhhhhssglvprgshmmsttlfkdftfeaahrlphvpeghkagrlhghsfmvrle
itgevdphtgwiidfaelkaafkptyerldhhylndipglenptsevlakwiwdqvkpvv
pllsavmvketctagciyrge

    Sequence, based on observed residues (ATOM records): (download) 
    >3qnaB (B:)
sttlfkdftfeaahrlphvpeghkagrlhghsfmvrleitgevdphtgwiidfaelkaaf
kptyerldhhylndipglenptsevlakwiwdqvkpvvpllsavmvketctagciyrg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3qnaC (C:)
mgsshhhhhhssglvprgshmmsttlfkdftfeaahrlphvpeghkagrlhghsfmvrle
itgevdphtgwiidfaelkaafkptyerldhhylndipglenptsevlakwiwdqvkpvv
pllsavmvketctagciyrge

    Sequence, based on observed residues (ATOM records): (download) 
    >3qnaC (C:)
sttlfkdftfeaahrlphvpeghkagrlhghsfmvrleitgevdphtgwiidfaelkaaf
kptyerldhhylndipglenptsevlakwiwdqvkpvvpllsavmvketctagciyrg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >3qnaD (D:)
mgsshhhhhhssglvprgshmmsttlfkdftfeaahrlphvpeghkagrlhghsfmvrle
itgevdphtgwiidfaelkaafkptyerldhhylndipglenptsevlakwiwdqvkpvv
pllsavmvketctagciyrge

    Sequence, based on observed residues (ATOM records): (download) 
    >3qnaD (D:)
sttlfkdftfeaahrlphvpeghkagrlhghsfmvrleitgevdphtgwiidfaelkaaf
kptyerldhhylndipglenptsevlakwiwdqvkpvvpllsavmvketctagciyrg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >3qnaE (E:)
mgsshhhhhhssglvprgshmmsttlfkdftfeaahrlphvpeghkagrlhghsfmvrle
itgevdphtgwiidfaelkaafkptyerldhhylndipglenptsevlakwiwdqvkpvv
pllsavmvketctagciyrge

    Sequence, based on observed residues (ATOM records): (download) 
    >3qnaE (E:)
sttlfkdftfeaahrlphvpeghkagrlhghsfmvrleitgevdphtgwiidfaelkaaf
kptyerldhhylndipglenptsevlakwiwdqvkpvvpllsavmvketctagciyrg

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >3qnaF (F:)
mgsshhhhhhssglvprgshmmsttlfkdftfeaahrlphvpeghkagrlhghsfmvrle
itgevdphtgwiidfaelkaafkptyerldhhylndipglenptsevlakwiwdqvkpvv
pllsavmvketctagciyrge

    Sequence, based on observed residues (ATOM records): (download) 
    >3qnaF (F:)
sttlfkdftfeaahrlphvpeghkagrlhghsfmvrleitgevdphtgwiidfaelkaaf
kptyerldhhylndipglenptsevlakwiwdqvkpvvpllsavmvketctagciyrg