PDB entry 3qeg
View 3qeg on RCSB PDB site
Description: Crystal structure of human N12-i2 Fab, an ADCC and neutralizing anti-HIV-1 Env antibody
Class: immune system
Keywords: ADCC and neutralizing anti-HIV-1 Env antibody N12-i2, CD4i antibody, Fab fragment, binds to viral glycoprotein gp120, IMMUNE SYSTEM
Deposited on
2011-01-20, released
2012-01-25
The last revision prior to the SCOPe 2.04 freeze date was dated
2012-01-25, with a file datestamp of
2012-01-20.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.205
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'H':
Compound: Fab fragment of human anti-HIV antibody N12-i2, heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Chain 'L':
Compound: Fab fragment of human anti-HIV antibody N12-i2, light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3qegl1, d3qegl2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'H':
No sequence available.
- Chain 'L':
Sequence, based on SEQRES records: (download)
>3qegL (L:)
eivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgip
drfsgsgsgtdftltisrlepedfavyycqqygsspetfgqgtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec
Sequence, based on observed residues (ATOM records): (download)
>3qegL (L:)
eivmmqspgtlslspgeratlscrasqsvsssylawyqqkpgqaprlliygassratgip
drfsgsgsgtdftltisrlepedfavyycqqygsspetfgqgtkveikrtvaapsvfifp
psdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrg