PDB entry 3qcy

View 3qcy on RCSB PDB site
Description: Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 4-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-N-phenyl-2-morpholinecarboxamide
Class: transferase/transferase inhibitor
Keywords: kinase domain, AGC kinase, signal transduction, Phosphoinositide, Phosphorylation on S241, TRANSFERASE-TRANSFERASE INHIBITOR complex
Deposited on 2011-01-17, released 2011-03-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.181
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide-dependent protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PDK1, PDPK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3qcya_
  • Heterogens: GOL, SO4, 3Q3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qcyA (A:)
gpamdgtaaeprpgagslqhaqpppqprkkrpedfkfgkilgegsfstvvlarelatsre
yaikilekrhiikenkvpyvtrerdvmsrldhpffvklyftfqddeklyfglsyakngel
lkyirkigsfdetctrfytaeivsaleylhgkgiihrdlkpenillnedmhiqitdfgta
kvlspeskqaransfvgtaqyvspellteksackssdlwalgciiyqlvaglppfragne
ylifqkiikleydfpekffpkardlvekllvldatkrlgceemegygplkahpffesvtw
enlhqqtppklt

    Sequence, based on observed residues (ATOM records): (download) 
    >3qcyA (A:)
qprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtrerd
vmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeivsa
leylhgkgiihrdlkpenillnedmhiqitdfgtakvlsvgtaqyvspellteksackss
dlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlvekllvldatk
rlgceemegygplkahpffesvtwenlhqqtppkl