PDB entry 3qcf

View 3qcf on RCSB PDB site
Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization
Class: hydrolase/hydrolase inhibitor
Keywords: TYROSINE RECEPTOR PHOSPHATASE, TWISTED MIXED BETA-SHEETS FLANKED BY {ALPHA}-HELICES, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2011-01-16, released 2011-12-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-12-28, with a file datestamp of 2011-12-23.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.265
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-type tyrosine-protein phosphatase gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPG, PTPRG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qcfa_
  • Chain 'B':
    Compound: Receptor-type tyrosine-protein phosphatase gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPG, PTPRG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3qcfb_
  • Heterogens: NXY, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3qcfA (A:)
gshmgsmeaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhkn
ryinilaydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrm
iweqntgiivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirn
tkvkkgqkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlv
hcsagvgrtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalle
ailgketevs

    Sequence, based on observed residues (ATOM records): (download) 
    >3qcfA (A:)
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntgi
ivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntknervvi
qyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsmlqq
ikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3qcfB (B:)
gshmgsmeaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhkn
ryinilaydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrm
iweqntgiivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirn
tkvkkgqkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlv
hcsagvgrtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalle
ailgketevs

    Sequence, based on observed residues (ATOM records): (download) 
    >3qcfB (B:)
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgkskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntg
iivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntknervv
iqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsmlq
qikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailg