SCOPe 2.08: Domain d3qcfa_: 3qcf A:

Lineage for d3qcfa_ (3qcf A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (140 PDB entries)

8. Domain d3qcfa_: 3qcf A: [215156]
   automated match to d1yfoa_
   complexed with nxy, so4

Details for d3qcfa_

PDB Entry: 3qcf, 2.5 Å

PDB Description: Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization

PDB Compounds: (A:) Receptor-type tyrosine-protein phosphatase gamma

SCOPe Domain Sequences for d3qcfa_:

Sequence, based on SEQRES records:

>d3qcfa_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgkdskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqnt
giivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntkvkkg
qkgnpkgrqnervviqyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagv
grtgtyividsmlqqikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

Sequence, based on observed residues (ATOM records):

>d3qcfa_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
meaipvkqfvkhigelysnnqhgfsedfeevqrctadmnitaehsnhpenkhknryinil
aydhsrvklrplpgskhsdyinanyvdgynkakayiatqgplkstfedfwrmiweqntgi
ivmitnlvekgrrkcdqywptenseeygniivtlkstkihacytvrrfsirntknervvi
qyhytqwpdmgvpeyalpvltfvrrssaarmpetgpvlvhcsagvgrtgtyividsmlqq
ikdkstvnvlgflkhirtqrnylvqteeqyifihdalleailgk

Timeline for d3qcfa_:

• d3qcfa_ first appeared in SCOPe 2.03
  
• d3qcfa_ appears in SCOPe 2.07