PDB entry 3og8
View 3og8 on RCSB PDB site
Description: Crystal structure of human RIG-I CTD bound to a 14-bp blunt-ended dsRNA
Class: hydrolase/RNA
Keywords: Innate immunity, viral RNA sensing, RNA binding domain, IPS-1, cytosolic, HYDROLASE-RNA complex
Deposited on
2010-08-16, released
2010-11-03
The last revision prior to the SCOPe 2.08 freeze date was dated
2011-03-23, with a file datestamp of
2011-03-18.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.217
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: ATP-dependent RNA helicase DDX58
Species: Homo sapiens [TaxId:9606]
Gene: DDX58
Database cross-references and differences (RAF-indexed):
- Uniprot O95786 (Start-124)
- engineered mutation (28)
- expression tag (125-127)
Domains in SCOPe 2.08: d3og8a1, d3og8a2 - Chain 'B':
Compound: ATP-dependent RNA helicase DDX58
Species: Homo sapiens [TaxId:9606]
Gene: DDX58
Database cross-references and differences (RAF-indexed):
- Uniprot O95786 (1-124)
- expression tag (0)
- engineered mutation (28)
- expression tag (125-127)
Domains in SCOPe 2.08: d3og8b1, d3og8b2, d3og8b3 - Chain 'C':
Compound: RNA (5'-r(*gp*gp*cp*gp*cp*gp*cp*gp*cp*gp*cp*gp*cp*c)-3')
- Chain 'D':
Compound: RNA (5'-r(*gp*gp*cp*gp*cp*gp*cp*gp*cp*gp*cp*gp*cp*c)-3')
- Heterogens: ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3og8A (A:)
mdkenkkllcrkckalacytadvrvieeshytvlgdafkecfvsrphpkpkqfssfekra
kifcarqncshdwgihvkyktfeipvikiesfvvediatgvqtlyskwkdfhfekipfdp
aemskleh
Sequence, based on observed residues (ATOM records): (download)
>3og8A (A:)
kenkkllcrkckalacytadvrvieeshytvlgdafkecfvsrphpkpkqfssfekraki
fcarqncshdwgihvkyktfeipvikiesfvvediatgvqtlyskwkdfhfekipfdpae
mskleh
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>3og8B (B:)
mdkenkkllcrkckalacytadvrvieeshytvlgdafkecfvsrphpkpkqfssfekra
kifcarqncshdwgihvkyktfeipvikiesfvvediatgvqtlyskwkdfhfekipfdp
aemskleh
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.