SCOPe 2.02: Structural Classification of Proteins

PDB entry 3n83

View 3n83 on RCSB PDB site
Description: T244A mutant of human mitochondrial aldehyde dehydrogenase, NAD complex
Class: oxidoreductase
Keywords: oxidoreductase, ALDH, Rossmann fold
Deposited on 2010-05-27, released 2011-04-13
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-04-13, with a file datestamp of 2011-04-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.191
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83a_
Chain 'B':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83b_
Chain 'C':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83c_
Chain 'D':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83d_
Chain 'E':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83e_
Chain 'F':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83f_
Chain 'G':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83g_
Chain 'H':
Compound: aldehyde dehydrogenase, mitochondrial
Species: Homo sapiens [TaxId:9609]
Gene: ALDH2, ALDM
Database cross-references and differences (RAF-indexed):
- Uniprot P05091 (Start-499)
  - engineered mutation (243)
Domains in SCOPe 2.02: d3n83h_
Heterogens: NA, GAI, EDO, ADP, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>3n83A (A:)
saaatqavpapnqqpevfcnqifinnewhdavsrktfptvnpstgevicqvaegdkedvd
kavkaaraafqlgspwrrmdashrgrllnrladlierdrtylaaletldngkpyvisylv
dldmvlkclryyagwadkyhgktipidgdffsytrhepvgvcgqiipwnfpllmqawklg
palatgnvvvmkvaeqtpltalyvanlikeagfppgvvnivpgfgptagaaiashedvdk
vafagsteigrviqvaagssnlkrvtlelggkspniimsdadmdwaveqahfalffnqgq
cccagsrtfvqediydefversvaraksrvvgnpfdskteqgpqvdetqfkkilgyintg
kqegakllcgggiaadrgyfiqptvfgdvqdgmtiakeeifgpvmqilkfktieevvgra
nnstyglaaavftkdldkanylsqalqagtvwvncydvfgaqspfggykmsgsgrelgey
glqaytevktvtvkvpqkns