PDB entry 3mne
View 3mne on RCSB PDB site
Description: Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by F608S mutation at 1.96A
Class: hormone receptor
Keywords: protein-ligand complex, steroid nuclear receptor, mouse, agonist, co-activator, HORMONE RECEPTOR
Deposited on
2010-04-21, released
2010-09-15
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-01-19, with a file datestamp of
2011-01-14.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.153
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Glucocorticoid receptor
Species: Mus musculus [TaxId:10090]
Gene: Nr3c1, Grl, Grl1
Database cross-references and differences (RAF-indexed):
- Uniprot P06537 (4-260)
- expression tag (3)
- engineered mutation (85)
Domains in SCOPe 2.04: d3mnea_ - Chain 'B':
Compound: Nuclear receptor coactivator 2 peptide
Species: synthetic, synthetic [TaxId:10090]
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, DEX, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3mneA (A:)
gshmvpaalpqltptlvslleviepevlyagydssvpdsawrimttlnmlggrqviaavk
wakaipgfrnlhlddqmtllqyswmslmafalgwrsyrqasgnllcfapdliineqrmtl
pcmydqckhmlfistelqrlqvsyeeylcmktllllssvpkeglksqelfdeirmtyike
lgkaivkregnssqnwqrfyqltklldsmhdvvenllsycfqtfldksmsiefpemlaei
itnqipkysngnikkllfhqk
Sequence, based on observed residues (ATOM records): (download)
>3mneA (A:)
mvpaalpqltptlvslleviepevlyagpdsawrimttlnmlggrqviaavkwakaipgf
rnlhlddqmtllqyswmslmafalgwrsyrqasgnllcfapdliineqrmtlpcmydqck
hmlfistelqrlqvsyeeylcmktllllssvpkeglksqelfdeirmtyikelgkaivkr
egnssqnwqrfyqltklldsmhdvvenllsycfqtfldksmsiefpemlaeiitnqipky
sngnikkllfhqk
- Chain 'B':
No sequence available.