PDB entry 3mbc

View 3mbc on RCSB PDB site
Description: Crystal structure of monomeric isocitrate dehydrogenase from Corynebacterium glutamicum in complex with NADP
Class: oxidoreductase
Keywords: Holoenzyme, Apoenzyme, Open conformation, NADP, Glyoxylate bypass, Magnesium, Metal-binding, Oxidoreductase, Tricarboxylic acid cycle
Deposited on 2010-03-25, released 2011-04-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-11-02, with a file datestamp of 2011-10-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.191
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Corynebacterium glutamicum [TaxId:196627]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3mbca_
  • Chain 'B':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Corynebacterium glutamicum [TaxId:196627]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3mbcb_
  • Heterogens: MG, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3mbcA (A:)
makiiwtrtdeapllatyslkpvveafaatagievetrdislagrilaqfperltedqkv
gnalaelgelaktpeaniiklpnisasvpqlkaaikelqdqgydipelpdnattdeekdi
larynavkgsavnpvlregnsdrrapiavknfvkkfphrmgewsadsktnvatmdandfr
hneksiildaadevqikhiaadgtetilkdslkllegevldgtvlsakaldaflleqvar
akaegilfsahlkatmmkvsdpiifghvvrayfadvfaqygeqllaaglngenglaails
glesldngeeikaafekgledgpdlamvnsargitnlhvpsdvivdasmpamirtsghmw
nkddqeqdtlaiipdssyagvyqtviedcrkngafdpttmgtvpnvglmaqkaeeygshd
ktfrieadgvvqvvssngdvliehdveandiwracqvkdapiqdwvklavtrsrlsgmpa
vfwldperahdrnlaslvekyladhdtegldiqilspveatqlsidrirrgedtisvtgn
vlrdyntdlfpilelgtsakmlsvvplmaggglfetgaggsapkhvqqvqeenhlrwdsl
geflalaesfrhelnnngntkagvladaldkatekllneekspsrkvgeidnrgshfwlt
kfwadelaaqtedadlaatfapvaealntgaadidaallavqggatdlggyyspneeklt
nimrpvaqfneivdalkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3mbcA (A:)
akiiwtrtdeapllatyslkpvveafaatagievetrdislagrilaqfperltedqkvg
nalaelgelaktpeaniiklpnisasvpqlkaaikelqdqgydipelpdnattdeekdil
arynavkgsavnpvlregnsdrrapiavknfvkkfphrmgewsadsktnvatmdandfrh
neksiildaadevqikhiaadgtetilkdslkllegevldgtvlsakaldaflleqvara
kaegilfsahlkatmmkvsdpiifghvvrayfadvfaqygeqllaaglngenglaailsg
lesldngeeikaafekgledgpdlamvnsargitnlhvpsdvivdasmpamirtsghmwn
kddqeqdtlaiipdssyagvyqtviedcrkngafdpttmgtvpnvglmaqkaeeygshdk
tfrieadgvvqvvssngdvliehdveandiwracqvkdapiqdwvklavtrsrlsgmpav
fwldperahdrnlaslvekyladhdtegldiqilspveatqlsidrirrgedtisvtgnv
lrdyntdlfpilelgtsakmlsvvplmaggglfetgaggsapkhvqqvqeenhlrwdslg
eflalaesfrhelnnngntkagvladaldkatekllneekspsrkvgeidnrgshfwltk
fwadelaaqtedadlaatfapvaealntgaadidaallavqggatdlggyyspneekltn
imrpvaqfneivdal

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3mbcB (B:)
makiiwtrtdeapllatyslkpvveafaatagievetrdislagrilaqfperltedqkv
gnalaelgelaktpeaniiklpnisasvpqlkaaikelqdqgydipelpdnattdeekdi
larynavkgsavnpvlregnsdrrapiavknfvkkfphrmgewsadsktnvatmdandfr
hneksiildaadevqikhiaadgtetilkdslkllegevldgtvlsakaldaflleqvar
akaegilfsahlkatmmkvsdpiifghvvrayfadvfaqygeqllaaglngenglaails
glesldngeeikaafekgledgpdlamvnsargitnlhvpsdvivdasmpamirtsghmw
nkddqeqdtlaiipdssyagvyqtviedcrkngafdpttmgtvpnvglmaqkaeeygshd
ktfrieadgvvqvvssngdvliehdveandiwracqvkdapiqdwvklavtrsrlsgmpa
vfwldperahdrnlaslvekyladhdtegldiqilspveatqlsidrirrgedtisvtgn
vlrdyntdlfpilelgtsakmlsvvplmaggglfetgaggsapkhvqqvqeenhlrwdsl
geflalaesfrhelnnngntkagvladaldkatekllneekspsrkvgeidnrgshfwlt
kfwadelaaqtedadlaatfapvaealntgaadidaallavqggatdlggyyspneeklt
nimrpvaqfneivdalkk

    Sequence, based on observed residues (ATOM records): (download) 
    >3mbcB (B:)
akiiwtrtdeapllatyslkpvveafaatagievetrdislagrilaqfperltedqkvg
nalaelgelaktpeaniiklpnisasvpqlkaaikelqdqgydipelpdnattdeekdil
arynavkgsavnpvlregnsdrrapiavknfvkkfphrmgewsadsktnvatmdandfrh
neksiildaadevqikhiaadgtetilkdslkllegevldgtvlsakaldaflleqvara
kaegilfsahlkatmmkvsdpiifghvvrayfadvfaqygeqllaaglngenglaailsg
lesldngeeikaafekgledgpdlamvnsargitnlhvpsdvivdasmpamirtsghmwn
kddqeqdtlaiipdssyagvyqtviedcrkngafdpttmgtvpnvglmaqkaeeygshdk
tfrieadgvvqvvssngdvliehdveandiwracqvkdapiqdwvklavtrsrlsgmpav
fwldperahdrnlaslvekyladhdtegldiqilspveatqlsidrirrgedtisvtgnv
lrdyntdlfpilelgtsakmlsvvplmaggglfetgaggsapkhvqqvqeenhlrwdslg
eflalaesfrhelnnngntkagvladaldkatekllneekspsrkvgeidnrgshfwltk
fwadelaaqtedadlaatfapvaealntgaadidaallavqggatdlggyyspneekltn
imrpvaqfneivdal