PDB entry 3l6c

View 3l6c on RCSB PDB site
Description: X-ray crystal structure of rat serine racemase in complex with malonate a potent inhibitor
Class: isomerase
Keywords: pyridoxal phosphate, PLP, serine racemase, isomerase
Deposited on 2009-12-23, released 2010-01-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-05-12, with a file datestamp of 2010-05-07.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.219
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine racemase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Srr
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q76EQ0
      • engineered (1)
      • engineered (5)
    Domains in SCOPe 2.06: d3l6ca_
  • Chain 'B':
    Compound: Serine racemase
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Srr
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q76EQ0
      • engineered (5)
    Domains in SCOPe 2.06: d3l6cb_
  • Heterogens: PLP, MN, MLI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3l6cA (A:)
mdaqydisfadvekahlniqdsvhltpvltssilnqiagrnlffkcelfqktgsfkirga
lnairglipdtlegkpkavvthssgnhgqaltyaaklegipayivvpqtapnckklaiqa
ygasivysepsdesrenvaqriiqetegilvhpnqepaviagqgtialevlnqvplvdal
vvpvggggmvagiaitiktlkpsvkvyaaepsnaddcyqsklkgeltpnlhppetiadgv
kssiglntwpiirdlvddvftvtedeikyatqlvwermkllieptagvglaavlsqhfqt
vspevknicivlsggnvdltslswvkqaerpaphhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3l6cA (A:)
daqydisfadvekahlniqdsvhltpvltssilnqiagrnlffkcelfqktgsfkirgal
nairglipdtlegkpkavvthssgnhgqaltyaaklegipayivvpqtapnckklaiqay
gasivysepsdesrenvaqriiqetegilvhpnqepaviagqgtialevlnqvplvdalv
vpvggggmvagiaitiktlkpsvkvyaaepsnaddcyqsklkgeltpnlhppetiadgvk
ssiglntwpiirdlvddvftvtedeikyatqlvwermkllieptagvglaavlsqhfqtv
spevknicivlsggnvdltsls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3l6cB (B:)
mdaqydisfadvekahlniqdsvhltpvltssilnqiagrnlffkcelfqktgsfkirga
lnairglipdtlegkpkavvthssgnhgqaltyaaklegipayivvpqtapnckklaiqa
ygasivysepsdesrenvaqriiqetegilvhpnqepaviagqgtialevlnqvplvdal
vvpvggggmvagiaitiktlkpsvkvyaaepsnaddcyqsklkgeltpnlhppetiadgv
kssiglntwpiirdlvddvftvtedeikyatqlvwermkllieptagvglaavlsqhfqt
vspevknicivlsggnvdltslswvkqaerpaphhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3l6cB (B:)
qydisfadvekahlniqdsvhltpvltssilnqiagrnlffkcelfqktgsfkirgalna
irgpkavvthssgnhgqaltyaaklegipayivvpqtapnckklaiqaygasivysepsd
esrenvaqriiqetegilvhpnqepaviagqgtialevlnqvplvdalvvpvggggmvag
iaitiktlkpsvkvyaaepsnaddcyqsklkgeltpnlhppetiadgvkssiglntwpii
rdlvddvftvtedeikyatqlvwermkllieptagvglaavlsqhfqtvspevknicivl
sggnvdltslsw