PDB entry 3kfx

View 3kfx on RCSB PDB site
Description: Human dCK complex with 5-Me dC and ADP
Class: transferase
Keywords: Human dCK, Nucleotide Kinase, P-Loop, 5-Me dC, ATP-binding, Kinase, Nucleotide-binding, Nucleus, Phosphoprotein, Transferase
Deposited on 2009-10-28, released 2010-09-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2010-09-15, with a file datestamp of 2010-09-10.
Experiment type: XRAY
Resolution: 1.96 Å
R-factor: 0.193
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Deoxycytidine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27707 (Start-278)
      • engineered (63)
      • engineered (77)
      • engineered (164)
    Domains in SCOPe 2.06: d3kfxa_
  • Chain 'B':
    Compound: Deoxycytidine kinase
    Species: Homo sapiens [TaxId:9606]
    Gene: DCK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27707 (Start-278)
      • engineered (63)
      • engineered (77)
      • engineered (164)
    Domains in SCOPe 2.06: d3kfxb_
  • Heterogens: ADP, MCY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3kfxA (A:)
mgsshhhhhhsglvprgshmatppkrsspsfsassegtrikkisiegniaagkstfvnil
kqlsedwevvpepvarwsnvqstqdefeeltmsqknggnvlqmmyekperwsftfqtyac
lsriraqlaslngklkdaekpvlffersvysdryifasnlyesesmnetewtiyqdwhdw
mnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykheswllhrtl
ktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

    Sequence, based on observed residues (ATOM records): (download) 
    >3kfxA (A:)
trikkisiegniaagkstfvnilkqlsedwevvpepvarwsnvqstnggnvlqmmyekpe
rwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifasnlyesesmnet
ewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhy
kheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3kfxB (B:)
mgsshhhhhhsglvprgshmatppkrsspsfsassegtrikkisiegniaagkstfvnil
kqlsedwevvpepvarwsnvqstqdefeeltmsqknggnvlqmmyekperwsftfqtyac
lsriraqlaslngklkdaekpvlffersvysdryifasnlyesesmnetewtiyqdwhdw
mnnqfgqsleldgiiylqatpetclhriylrgrneeqgipleyleklhykheswllhrtl
ktnfdylqevpiltldvnedfkdkyeslvekvkeflstl

    Sequence, based on observed residues (ATOM records): (download) 
    >3kfxB (B:)
rikkisiegniaagkstfvnilkqlsedwevvpepvarwsnvqstqdefeeltmsqkngg
nvlqmmyekperwsftfqtyaclsriraqlaslngklkdaekpvlffersvysdryifas
nlyesesmnetewtiyqdwhdwmnnqfgqsleldgiiylqatpetclhriylrgrneeqg
ipleyleklhykheswllhrtlktnfdylqevpiltldvnedfkdkyeslvekvkeflst
l