PDB entry 3ix9

View 3ix9 on RCSB PDB site
Description: Crystal structure of Streptococcus pneumoniae dihydrofolate reductase - Sp9 mutant
Class: oxidoreductase
Keywords: Central beta sheet surrounded by 4 alpha helices, Oxidoreductase
Deposited on 2009-09-03, released 2010-02-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2010-02-02, with a file datestamp of 2010-01-29.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.237
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: dfr
    Database cross-references and differences (RAF-indexed):
    • Uniprot O85261
      • engineered (45)
      • engineered (79)
      • engineered (96-97)
      • engineered (100)
      • engineered (110)
      • engineered (119)
      • engineered (152)
      • engineered (168)
    Domains in SCOPe 2.05: d3ix9a_
  • Chain 'B':
    Compound: dihydrofolate reductase
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: dfr
    Database cross-references and differences (RAF-indexed):
    • Uniprot O85261
      • engineered (45)
      • engineered (79)
      • engineered (96-97)
      • engineered (100)
      • engineered (110)
      • engineered (119)
      • engineered (152)
      • engineered (168)
    Domains in SCOPe 2.05: d3ix9b_
  • Heterogens: NDP, MTX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ix9A (A:)
mkhhhhhhhhgglvprgshgmtkkivaiwaqdeegvigkdnrlpwylpaelqhfkettln
hailmgrvtfdgmgrrllpkretliltrnpeekidgvatfhdvqsvldwysaqeknlyiv
ggkqifqafepyldevivthiharvegdtyfpaefdlslfetvsskfytkdeknpydfti
qyrkrkevle

    Sequence, based on observed residues (ATOM records): (download) 
    >3ix9A (A:)
tkkivaiwaqdeegvigkdnrlpwylpaelqhfkettlnhailmgrvtfdgmgrrllpkr
etliltrnpeekidgvatfhdvqsvldwysaqeknlyivggkqifqafepyldevivthi
harvegdtyfpaefdlslfetvsskfytkdeknpydftiqyrkrke

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ix9B (B:)
mkhhhhhhhhgglvprgshgmtkkivaiwaqdeegvigkdnrlpwylpaelqhfkettln
hailmgrvtfdgmgrrllpkretliltrnpeekidgvatfhdvqsvldwysaqeknlyiv
ggkqifqafepyldevivthiharvegdtyfpaefdlslfetvsskfytkdeknpydfti
qyrkrkevle

    Sequence, based on observed residues (ATOM records): (download) 
    >3ix9B (B:)
tkkivaiwaqdeegvigkdnrlpwylpaelqhfkettlnhailmgrvtfdgmgrrllpkr
etliltrnpeekidgvatfhdvqsvldwysaqeknlyivggkqifqafepyldevivthi
harvegdtyfpaefdlslfetvsskfytkdeknpydftiqyrkrke