PDB entry 3iuc

View 3iuc on RCSB PDB site
Description: Crystal structure of the human 70kDa heat shock protein 5 (BiP/GRP78) ATPase domain in complex with ADP
Class: chaperone
Keywords: helix, Structural Genomics, Structural Genomics Consortium, SGC, ATP-binding, Nucleotide-binding, Stress response, CHAPERONE
Deposited on 2009-08-31, released 2009-09-22
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-02-02, with a file datestamp of 2010-01-29.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.194
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3iuca1, d3iuca2
  • Chain 'C':
    Compound: Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B0QZ61 (23-End)
      • expression tag (16-22)
    Domains in SCOPe 2.04: d3iucc1, d3iucc2
  • Heterogens: ADP, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3iucA (A:)
mhhhhhhssgvdlgtenlyfqsmdvgtvvgidlgttyscvgvfkngrveiiandqgnrit
psyvaftpegerligdaaknqltsnpentvfdakrligrtwndpsvqqdikflpfkvvek
ktkpyiqvdigggqtktfapeeisamvltkmketaeaylgkkvthavvtvpayfndaqrq
atkdagtiaglnvmriineptaaaiaygldkregeknilvfdlgggtfdvslltidngvf
evvatngdthlggedfdqrvmehfiklykkktgkdvrkdnravqklrrevekakralssq
hqarieiesfyegedfsetltrakfeelnmdlfrstmkpvqkvledsdlkksdideivlv
ggstripkiqqlvkeffngkepsrginpdeavaygaavqagvlsgdqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3iucA (A:)
gtvvgidlgttyscvgvfkngrveiiandqgnritpsyvaftpegerligdaaknqltsn
pentvfdakrligrtwndpsvqqdikflpfkvvekktkpyiqvdigggqtktfapeeisa
mvltkmketaeaylgkkvthavvtvpayfndaqrqatkdagtiaglnvmriineptaaai
aygldkregeknilvfdlgggtfdvslltidngvfevvatngdthlggedfdqrvmehfi
klykkktgkdvrkdnravqklrrevekakralssqhqarieiesfyegedfsetltrakf
eelnmdlfrstmkpvqkvledsdlkksdideivlvggstripkiqqlvkeffngkepsrg
inpdeavaygaavqagvls

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >3iucC (C:)
mhhhhhhssgvdlgtenlyfqsmdvgtvvgidlgttyscvgvfkngrveiiandqgnrit
psyvaftpegerligdaaknqltsnpentvfdakrligrtwndpsvqqdikflpfkvvek
ktkpyiqvdigggqtktfapeeisamvltkmketaeaylgkkvthavvtvpayfndaqrq
atkdagtiaglnvmriineptaaaiaygldkregeknilvfdlgggtfdvslltidngvf
evvatngdthlggedfdqrvmehfiklykkktgkdvrkdnravqklrrevekakralssq
hqarieiesfyegedfsetltrakfeelnmdlfrstmkpvqkvledsdlkksdideivlv
ggstripkiqqlvkeffngkepsrginpdeavaygaavqagvlsgdqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3iucC (C:)
nlyfqsmdvgtvvgidlgttyscvgvfkngrveiiandqgnritpsyvaftpegerligd
aaknqltsnpentvfdakrligrtwndpsvqqdikflpfkvvekktkpyiqvdigggqtk
tfapeeisamvltkmketaeaylgkkvthavvtvpayfndaqrqatkdagtiaglnvmri
ineptaaaiaygldkgeknilvfdlgggtfdvslltidngvfevvatngdthlggedfdq
rvmehfiklykkktgkdvrkdnravqklrrevekakralssqhqarieiesfyegedfse
tltrakfeelnmdlfrstmkpvqkvledsdlkksdideivlvggstripkiqqlvkeffn
gkepsrginpdeavaygaavqagvlsgd