PDB entry 3ioh

View 3ioh on RCSB PDB site
Description: Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A)
Class: transferase
Keywords: GTA, ABO, cisAB mutant, AA(Gly)B, ROSSMANN FOLD, UNLIGANDED, OPEN CONFORMATION, BLOOD GROUP ANTIGEN, GLYCOPROTEIN, GLYCOSYLTRANSFERASE, GOLGI APPARATUS, MANGANESE, MEMBRANE, METAL-BINDING, SECRETED, SIGNAL-ANCHOR, TRANSFERASE, TRANSMEMBRANE
Deposited on 2009-08-14, released 2010-04-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: 0.153
AEROSPACI score: 0.72 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histo-blood group ABO system transferase
    Species: Homo sapiens [TaxId:9606]
    Gene: ABO
    Database cross-references and differences (RAF-indexed):
    • Uniprot P16442 (7-End)
      • expression tag (6)
      • engineered (209)
      • engineered (211)
    Domains in SCOPe 2.07: d3ioha1, d3ioha2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3iohA (A:)
maigefmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqntti
gltvfaikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevr
aykrwqdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgf
ygssreaftyerrpqsqayipkdegdfyyggaffggsvqevqrltrachqammvdqangi
eavwhdeshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavpknhqavrnp

    Sequence, based on observed residues (ATOM records): (download) 
    >3iohA (A:)
mvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvfa
ikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevraykrwq
dvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpgfygssre
aftyerrpqsqayipkdegdfyyggaffggsvqevqrltrachqammvdqangieavwhd
eshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp