PDB entry 3hsv

View 3hsv on RCSB PDB site
Description: Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2
Class: protein binding, ligase
Keywords: ubiquitin, E3, SPOP, MacroH2A, Nucleus, Ubl conjugation pathway, Alternative splicing, Chromatin regulator, Chromosomal protein, DNA-binding, Isopeptide bond, Methylation, Nucleosome core, Phosphoprotein, Ubl conjugation, ligase, protein binding
Deposited on 2009-06-10, released 2009-10-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-10-27, with a file datestamp of 2009-10-23.
Experiment type: XRAY
Resolution: 1.43 Å
R-factor: 0.175
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Speckle-type POZ protein
    Species: Pongo abelii [TaxId:9601]
    Gene: SPOP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5NVK7 (6-End)
      • engineered (118)
    Domains in SCOPe 2.06: d3hsva_
  • Chain 'B':
    Compound: Speckle-type POZ protein
    Species: Pongo abelii [TaxId:9601]
    Gene: SPOP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5NVK7 (6-End)
      • engineered (118)
    Domains in SCOPe 2.06: d3hsvb_
  • Chain 'M':
    Compound: Core histone macro-H2A.1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3hsvA (A:)
gsggsgkvvkfsymwtinnfsfcreemgeviksstfssgandklkwclrvnpkgldeesk
dylslylllvscpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgf
lldeangllpddkltlfcevsvvqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3hsvA (A:)
kvvkfsymwtinnfsfcreemgeviksstfsslkwclrvnpkgldeeskdylslylllvs
cpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgflldeangllpd
dkltlfcevsvvq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3hsvB (B:)
gsggsgkvvkfsymwtinnfsfcreemgeviksstfssgandklkwclrvnpkgldeesk
dylslylllvscpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgf
lldeangllpddkltlfcevsvvqd

    Sequence, based on observed residues (ATOM records): (download) 
    >3hsvB (B:)
kvvkfsymwtinnfsfcreemgeviksstfsslkwclrvnpkgldeeskdylslylllvs
cpksevrakfkfsilnakgeetkamesqrayrfvqgkdwgfkkfirrgflldeangllpd
dkltlfcevsvv

  • Chain 'M':
    No sequence available.