PDB entry 3h8q

View 3h8q on RCSB PDB site
Description: Crystal structure of glutaredoxin domain of human thioredoxin reductase 3
Class: oxidoreductase
Keywords: oxidoreductase, Structural Genomics, Structural Genomics Consortium, SGC, Developmental protein, Differentiation, Disulfide bond, Electron transport, Endoplasmic reticulum, FAD, Flavoprotein, Microsome, NADP, Nucleus, Phosphoprotein, Redox-active center, Selenium, Selenocysteine, Spermatogenesis, Transport
Deposited on 2009-04-29, released 2009-05-12
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: 0.191
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thioredoxin reductase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: TGR, TRXR3, TXNRD3, TXNRD3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86VQ6 (1-106)
      • expression tag (0)
      • expression tag (107)
    Domains in SCOPe 2.01: d3h8qa_
  • Chain 'B':
    Compound: Thioredoxin reductase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: TGR, TRXR3, TXNRD3, TXNRD3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q86VQ6 (Start-106)
      • expression tag (107)
    Domains in SCOPe 2.01: d3h8qb_
  • Heterogens: SO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3h8qA (A:)
mareelrrhlvgliersrvvifsksycphstrvkelfsslgvecnvleldqvddgarvqe
vlseitnqktvpnifvnkvhvggcdqtfqayqsgllqkllqedlaydaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >3h8qA (A:)
mareelrrhlvgliersrvvifsksycphstrvkelfsslgvecnvleldqvddgarvqe
vlseitnqktvpnifvnkvhvggcdqtfqayqsgllqkllqedlayda

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3h8qB (B:)
mareelrrhlvgliersrvvifsksycphstrvkelfsslgvecnvleldqvddgarvqe
vlseitnqktvpnifvnkvhvggcdqtfqayqsgllqkllqedlaydaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >3h8qB (B:)
reelrrhlvgliersrvvifsksycphstrvkelfsslgvecnvleldqvddgarvqevl
seitnqktvpnifvnkvhvggcdqtfqayqsgllqkllqedlayda