PDB entry 3h62

View 3h62 on RCSB PDB site
Description: Catalytic domain of human Serine/Threonine Phosphatase 5 (PP5c) with two Mn2+ atoms complexed with cantharidic acid
Class: Hydrolase
Keywords: metalloenzyme, phosphatase, inhibitors, drug design, Cytoplasm, Hydrolase, Iron, Manganese, Metal-binding, Nucleus, Protein phosphatase, TPR repeat
Deposited on 2009-04-23, released 2009-09-29
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-09-29, with a file datestamp of 2009-09-25.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: 0.179
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase 5
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP5C, PPP5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3h62b_
  • Chain 'C':
    Compound: Serine/threonine-protein phosphatase 5
    Species: Homo sapiens [TaxId:9606]
    Gene: PPP5C, PPP5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3h62c_
  • Heterogens: MN, NHC, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3h62B (B:)
ysgpkledgkvtisfmkelmqwykdqkklhrkcayqilvqvkevlsklstlvettlkete
kitvcgdthgqfydllnifelnglpsetnpyifngdfvdrgsfsveviltlfgfkllypd
hfhllrgnhetdnmnqiygfegevkakytaqmyelfsevfewlplaqcingkvlimhggl
fsedgvtlddirkiernrqppdsgpmcdllwsdpqpqngrsiskrgvscqfgpdvtkafl
eennldyiirshevkaegyevahggrcvtvfsapnycdqmgnkasyihlqgsdlrpqfhq
ftavphpnvkpmaya

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3h62C (C:)
ysgpkledgkvtisfmkelmqwykdqkklhrkcayqilvqvkevlsklstlvettlkete
kitvcgdthgqfydllnifelnglpsetnpyifngdfvdrgsfsveviltlfgfkllypd
hfhllrgnhetdnmnqiygfegevkakytaqmyelfsevfewlplaqcingkvlimhggl
fsedgvtlddirkiernrqppdsgpmcdllwsdpqpqngrsiskrgvscqfgpdvtkafl
eennldyiirshevkaegyevahggrcvtvfsapnycdqmgnkasyihlqgsdlrpqfhq
ftavphpnvkpmaya