PDB entry 3gv7

View 3gv7 on RCSB PDB site
Description: Human DNA polymerase iota in complex with T template DNA and incoming dTTP
Class: transferase/DNA
Keywords: Y-family polymerase, polymerase iota, error prone replication, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Magnesium, Metal-binding, Mutator protein, Nucleotidyltransferase, Nucleus, Schiff base, Transferase, TRANSFERASE-DNA COMPLEX
Deposited on 2009-03-30, released 2009-06-02
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.21
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: DNA polymerase iota
    Species: Homo sapiens [TaxId:9606]
    Gene: POLI, RAD30B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3gv7b1, d3gv7b2
  • Chain 'P':
    Compound: 5'-d(*ap*gp*gp*ap*cp*cp*c)-3'
  • Chain 'T':
    Compound: 5'-d(p*ap*tp*gp*gp*gp*tp*cp*cp*t)-3'
  • Heterogens: MG, TTP, HOH

PDB Chain Sequences:

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3gv7B (B:)
meladvgaaassqgvhdqvlptpnassrvivhvdldcfyaqvemisnpelkdkplgvqqk
ylvvtcnyearklgvkklmnvrdakekcpqlvlvngedltryremsykvtelleefspvv
erlgfdenfvdltemvekrlqqlqsdelsavtvsghvynnqsinlldvlhirllvgsqia
aemreamynqlgltgcagvasnkllaklvsgvfkpnqqtvllpescqhlihslnhikeip
gigyktakclealginsvrdlqtfspkilekelgisvaqriqklsfgednspvilsgppq
sfseedsfkkcsseveaknkieellasllnrvcqdgrkphtvrliirryssekhygresr
qcpipshviqklgtgnydvmtpmvdilmklfrnmvnvkmpfhltllsvcfcnlkalntak

    Sequence, based on observed residues (ATOM records): (download) 
    >3gv7B (B:)
ssrvivhvdldcfyaqvemisnpelkdkplgvqqkylvvtcnyearklgvkklmnvrdak
ekcpqlvlvngedltryremsykvtelleefspvverlgfdenfvdltemvekrlqqlqs
delsavtvsghvynnqsinlldvlhirllvgsqiaaemreamynqlgltgcagvasnkll
aklvsgvfkpnqqtvllpescqhlihslnhikeipgigyktakclealginsvrdlqtfs
pkilekelgisvaqriqklsfgednspvilsgppqsfseedsfkkcsseveaknkieell
asllnrvcqdgrkphtvrliirrygresrqcpipshviqkdvmtpmvdilmklfrnmvnv
kmpfhltllsvcfcnlk

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.