PDB entry 3fnh
View 3fnh on RCSB PDB site
Description: Crystal structure of InhA bound to triclosan derivative
Class: oxidoreductase
Keywords: InhA, triclosan, tuberculosis, Antibiotic resistance, Fatty acid biosynthesis, Lipid synthesis, NAD, Oxidoreductase
Deposited on
2008-12-24, released
2009-01-20
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-17, with a file datestamp of
2009-02-13.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.223
AEROSPACI score: 0.19
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
Species: Mycobacterium tuberculosis [TaxId:1773]
Gene: inhA, Rv1484, MT1531, MTCY277.05
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d3fnha_ - Heterogens: NAD, JPJ, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3fnhA (A:)
mtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakapl
leldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgi
hisaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareag
kygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvak
tvcallsdwlpattgdiiyadggahtqll
Sequence, based on observed residues (ATOM records): (download)
>3fnhA (A:)
tglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakapll
eldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgih
isaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagk
ygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvakt
vcallsdwlpattgdiiyadggahtqll