PDB entry 3f9m

View 3f9m on RCSB PDB site
Description: Human pancreatic glucokinase in complex with glucose and activator showing a mobile flap
Class: transferase
Keywords: Glucokinase, Hexokinase IV, ATP-binding, Diabetes mellitus, Disease mutation, Glycolysis, Kinase, Nucleotide-binding, Transferase
Deposited on 2008-11-14, released 2008-12-02
The last revision prior to the SCOPe 2.04 freeze date was dated 2012-04-25, with a file datestamp of 2012-04-20.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.191
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35557 (16-End)
      • expression tag (8-15)
    Domains in SCOPe 2.04: d3f9ma1, d3f9ma2
  • Heterogens: GLC, MRK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3f9mA (A:)
mghhhhhhenlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasv
kmlptyvrstpegsevgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedam
tgtaemlfdyisecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasg
aegnnvvgllrdaikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacym
eemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekligg
kymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstl
glrpsttdcdivrracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvykl
hpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3f9mA (A:)
enlyfqgmkkekveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvr
stpegsevgdflsldlggtnfrvmlvkvgeqwsvktkhqmysipedamtgtaemlfdyis
ecisdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrd
aikrrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegd
egrmcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvll
rlvdenllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdiv
rracesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasv
rrltpsceitfieseegsgrgaalvsavack