PDB entry 3euf

View 3euf on RCSB PDB site
Description: Crystal structure of BAU-bound human uridine phosphorylase 1
Class: transferase
Keywords: nucleoside phosphorylase, uridine rescue, 5-benzylacyclouridine, Alternative splicing, Glycosyltransferase, Transferase
Deposited on 2008-10-10, released 2009-03-31
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-03-31, with a file datestamp of 2009-03-27.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.205
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridine phosphorylase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: UPP1, UP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3eufa_
  • Chain 'B':
    Compound: Uridine phosphorylase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: UPP1, UP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3eufb_
  • Chain 'C':
    Compound: Uridine phosphorylase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: UPP1, UP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3eufc_
  • Chain 'D':
    Compound: Uridine phosphorylase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: UPP1, UP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3eufd_
  • Heterogens: BAU, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3eufA (A:)
    mrgshhhhhhgspglqefmaatganaekaeshndcpvrllnpniakmkedilyhfnltts
    rhnfpalfgdvkfvcvggspsrmkafircvgaelgldcpgrdypnicagtdryamykvgp
    vlsvshgmgipsisimlhelikllyyarcsnvtiirigtsggiglepgtvviteqavdtc
    fkaefeqivlgkrvirktdlnkklvqelllcsaelsefttvvgntmctldfyegqgrldg
    alcsytekdkqayleaayaagvrniemessvfaamcsacglqaavvcvtllnrlegdqis
    sprnvlseyqqrpqrlvsyfikkklska
    

    Sequence, based on observed residues (ATOM records): (download)
    >3eufA (A:)
    dcpvrllnpniakmkedilyhfnlttsrhnfpalfgdvkfvcvggspsrmkafircvgae
    lgldcpgrdypnicagtdryamykvgpvlsvshgmgipsisimlhelikllyyarcsnvt
    iirigtsggiglepgtvviteqavdtcfkaefeqivlgkrvirktdlnkklvqelllcsa
    elsefttvvgntmctldfyegqgrldgalcsytekdkqayleaayaagvrniemessvfa
    amcsacglqaavvcvtllnrlegdqissprnvlseyqqrpqrlvsyfikkkls
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3eufB (B:)
    mrgshhhhhhgspglqefmaatganaekaeshndcpvrllnpniakmkedilyhfnltts
    rhnfpalfgdvkfvcvggspsrmkafircvgaelgldcpgrdypnicagtdryamykvgp
    vlsvshgmgipsisimlhelikllyyarcsnvtiirigtsggiglepgtvviteqavdtc
    fkaefeqivlgkrvirktdlnkklvqelllcsaelsefttvvgntmctldfyegqgrldg
    alcsytekdkqayleaayaagvrniemessvfaamcsacglqaavvcvtllnrlegdqis
    sprnvlseyqqrpqrlvsyfikkklska
    

    Sequence, based on observed residues (ATOM records): (download)
    >3eufB (B:)
    dcpvrllnpniakmkedilyhfnlttsrhnfpalfgdvkfvcvggspsrmkafircvgae
    lgldcpgrdypnicagtdryamykvgpvlsvshgmgipsisimlhelikllyyarcsnvt
    iirigtsggiglepgtvviteqavdtcfkaefeqivlgkrvirktdlnkklvqelllcsa
    elsefttvvgntmctldfyegqgrldgalcsytekdkqayleaayaagvrniemessvfa
    amcsacglqaavvcvtllnrlegdqissprnvlseyqqrpqrlvsyfikkkls
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3eufC (C:)
    mrgshhhhhhgspglqefmaatganaekaeshndcpvrllnpniakmkedilyhfnltts
    rhnfpalfgdvkfvcvggspsrmkafircvgaelgldcpgrdypnicagtdryamykvgp
    vlsvshgmgipsisimlhelikllyyarcsnvtiirigtsggiglepgtvviteqavdtc
    fkaefeqivlgkrvirktdlnkklvqelllcsaelsefttvvgntmctldfyegqgrldg
    alcsytekdkqayleaayaagvrniemessvfaamcsacglqaavvcvtllnrlegdqis
    sprnvlseyqqrpqrlvsyfikkklska
    

    Sequence, based on observed residues (ATOM records): (download)
    >3eufC (C:)
    dcpvrllnpniakmkedilyhfnlttsrhnfpalfgdvkfvcvggspsrmkafircvgae
    lgldcpgrdypnicagtdryamykvgpvlsvshgmgipsisimlhelikllyyarcsnvt
    iirigtsggiglepgtvviteqavdtcfkaefeqivlgkrvirktdlnkklvqelllcsa
    elsefttvvgntmctldfyegqgrldgalcsytekdkqayleaayaagvrniemessvfa
    amcsacglqaavvcvtllnrlegdqissprnvlseyqqrpqrlvsyfikkklsk
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >3eufD (D:)
    mrgshhhhhhgspglqefmaatganaekaeshndcpvrllnpniakmkedilyhfnltts
    rhnfpalfgdvkfvcvggspsrmkafircvgaelgldcpgrdypnicagtdryamykvgp
    vlsvshgmgipsisimlhelikllyyarcsnvtiirigtsggiglepgtvviteqavdtc
    fkaefeqivlgkrvirktdlnkklvqelllcsaelsefttvvgntmctldfyegqgrldg
    alcsytekdkqayleaayaagvrniemessvfaamcsacglqaavvcvtllnrlegdqis
    sprnvlseyqqrpqrlvsyfikkklska
    

    Sequence, based on observed residues (ATOM records): (download)
    >3eufD (D:)
    dcpvrllnpniakmkedilyhfnlttsrhnfpalfgdvkfvcvggspsrmkafircvgae
    lgldcpgrdypnicagtdryamykvgpvlsvshgmgipsisimlhelikllyyarcsnvt
    iirigtsggiglepgtvviteqavdtcfkaefeqivlgkrvirktdlnkklvqelllcsa
    elsefttvvgntmctldfyegqgrldgalcsytekdkqayleaayaagvrniemessvfa
    amcsacglqaavvcvtllnrlegdqissprnvlseyqqrpqrlvsyfikkklsk