PDB entry 3ehw

View 3ehw on RCSB PDB site
Description: Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
Class: hydrolase
Keywords: jelly-roll, full-length C-terminal arm, enzyme-ligand complex, HYDROLASE
Deposited on 2008-09-15, released 2008-09-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-03-07, with a file datestamp of 2012-03-02.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.16
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dUTP pyrophosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ehwa_
  • Chain 'B':
    Compound: dUTP pyrophosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ehwb_
  • Chain 'C':
    Compound: dUTP pyrophosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ehwc_
  • Chain 'X':
    Compound: dUTP pyrophosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ehwx_
  • Chain 'Y':
    Compound: dUTP pyrophosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ehwy_
  • Chain 'Z':
    Compound: dUTP pyrophosphatase
    Species: Homo sapiens [TaxId:9606]
    Gene: dut
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3ehwz_
  • Heterogens: MG, DUP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3ehwA (A:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehwA (A:)
    mqlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrva
    prsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeie
    evqalddtergsggfgstgkn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >3ehwB (B:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehwB (B:)
    qlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrvap
    rsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeiee
    vqalddtergsggfgstgkn
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >3ehwC (C:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehwC (C:)
    qlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrvap
    rsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeiee
    vqalddtergsggfgstgkn
    

  • Chain 'X':
    Sequence, based on SEQRES records: (download)
    >3ehwX (X:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehwX (X:)
    qlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrvap
    rsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeiee
    vqalddtergsggfgstgkn
    

  • Chain 'Y':
    Sequence, based on SEQRES records: (download)
    >3ehwY (Y:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehwY (Y:)
    qlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrvap
    rsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeiee
    vqalddtergsggfgstgkn
    

  • Chain 'Z':
    Sequence, based on SEQRES records: (download)
    >3ehwZ (Z:)
    mpcseetpaispskrarpaevggmqlrfarlsehataptrgsaraagydlysaydytipp
    mekavvktdiqialpsgcygrvaprsglaakhfidvgagvidedyrgnvgvvlfnfgkek
    fevkkgdriaqlicerifypeieevqalddtergsggfgstgkn
    

    Sequence, based on observed residues (ATOM records): (download)
    >3ehwZ (Z:)
    qlrfarlsehataptrgsaraagydlysaydytippmekavvktdiqialpsgcygrvap
    rsglaakhfidvgagvidedyrgnvgvvlfnfgkekfevkkgdriaqlicerifypeiee
    vqalddtergsggfgstgkn