PDB entry 3dds

View 3dds on RCSB PDB site
Description: Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261
Class: transferase
Keywords: GP, Glycogen Phosphorylase, Diabetes, Allosteric enzyme, Carbohydrate metabolism, Disease mutation, Glycogen metabolism, Glycogen storage disease, Glycosyltransferase, Nucleotide-binding, Phosphoprotein, Pyridoxal phosphate, Transferase
Deposited on 2008-06-06, released 2009-01-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen phosphorylase, liver form
    Species: Homo sapiens [TaxId:9606]
    Gene: PYGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ddsa_
  • Chain 'B':
    Compound: Glycogen phosphorylase, liver form
    Species: Homo sapiens [TaxId:9606]
    Gene: PYGL
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d3ddsb_
  • Heterogens: NBG, PO4, PLP, CFF, 26B, MPD, MES, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3ddsA (A:)
ggakpltdqekrrqisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalaht
vrdhlvgrwirtqqhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgld
ieeleeieedaglgngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqvee
addwlrygnpweksrpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnntv
ntmrlwsarapndfnlrdfnvgdyiqavldrnlaenisrvlypndnffegkelrlkqeyf
vvaatlqdiirrfkaskfgstrgagtvfdafpdqvaiqlndthpalaipelmrifvdiek
lpwskaweltqktfaytnhtvlpealerwpvdlvekllprhleiiyeinqkhldrivalf
pkdvdrlrrmslieeegskrinmahlcivgshavngvakihsdivktkvfkdfselepdk
fqnktngitprrwlllcnpglaeliaekigedyvkdlsqltklhsflgddvflrelakvk
qenklkfsqfleteykvkinpssmfdvqvkriheykrqllnclhvitmynrikkdpkklf
vprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsklkviflenyrvslaekvip
atdlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenlfifgmriddv
aaldkkgyeakeyyealpelklvidqidngffspkqpdlfkdiinmlfyhdrfkvfadye
ayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtikeyaqniwnvepsdlkislsn
esnkvngn

    Sequence, based on observed residues (ATOM records): (download) 
    >3ddsA (A:)
qisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtq
qhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedagl
gngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpwek
srpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapnd
gdyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskfgst
rgagtvfdafpdqvaiqlndthpalaipelmrifvdieklpwskaweltqktfaytnhtv
lpealerwpvdlvekllprhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskri
nmahlcivgshavngvakihsdivktkvfkdfselepdkfqnktngitprrwlllcnpgl
aeliaekigedyvkdlsqltklhsflgddvflrelakvkqenklkfsqfleteykvkinp
ssmfdvqvkriheykrqllnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmi
iklitsvadvvnndpmvgsklkviflenyrvslaekvipatdlseqistagteasgtgnm
kfmlngaltigtmdganvemaeeageenlfifgmriddvaaldkkgyeakeyyealpelk
lvidqidngffspkqpdlfkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawnt
mvlkniaasgkfssdrtikeyaqniwnveps

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3ddsB (B:)
ggakpltdqekrrqisirgivgvenvaelkksfnrhlhftlvkdrnvattrdyyfalaht
vrdhlvgrwirtqqhyydkcpkrvyylslefymgrtlqntminlglqnacdeaiyqlgld
ieeleeieedaglgngglgrlaacfldsmatlglaaygygiryeygifnqkirdgwqvee
addwlrygnpweksrpefmlpvhfygkvehtntgtkwidtqvvlalpydtpvpgymnntv
ntmrlwsarapndfnlrdfnvgdyiqavldrnlaenisrvlypndnffegkelrlkqeyf
vvaatlqdiirrfkaskfgstrgagtvfdafpdqvaiqlndthpalaipelmrifvdiek
lpwskaweltqktfaytnhtvlpealerwpvdlvekllprhleiiyeinqkhldrivalf
pkdvdrlrrmslieeegskrinmahlcivgshavngvakihsdivktkvfkdfselepdk
fqnktngitprrwlllcnpglaeliaekigedyvkdlsqltklhsflgddvflrelakvk
qenklkfsqfleteykvkinpssmfdvqvkriheykrqllnclhvitmynrikkdpkklf
vprtviiggkaapgyhmakmiiklitsvadvvnndpmvgsklkviflenyrvslaekvip
atdlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenlfifgmriddv
aaldkkgyeakeyyealpelklvidqidngffspkqpdlfkdiinmlfyhdrfkvfadye
ayvkcqdkvsqlymnpkawntmvlkniaasgkfssdrtikeyaqniwnvepsdlkislsn
esnkvngn

    Sequence, based on observed residues (ATOM records): (download) 
    >3ddsB (B:)
nvaelkksfnrhlhftlvkdrnvattrdyyfalahtvrdhlvgrwirtqqhyydkcpkrv
yylslefymgrtlqntminlglqnacdeaiyqlgldieeleeieedaglgngglgrlaac
fldsmatlglaaygygiryeygifnqkirdgwqveeaddwlrygnpweksrpefmlpvhf
ygkvehtntgtkwidtqvvlalpydtpvpgymnntvntmrlwsarapndfnlrdgdyiqa
vldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfkaskfgstgtvfda
fpdqvaiqlndthpalaipelmrifvdieklpwskaweltqktfaytnhtvlpealerwp
vdlvekllprhleiiyeinqkhldrivalfpkdvdrlrrmslieeegskrinmahlcivg
shavngvakihsdivktkvfkdfselepdkfqnktngitprrwlllcnpglaeliaekig
edyvkdlsqltklhsflgddvflrelakvkqenklkfsqfleteykvkinpssmfdvqvk
riheykrqllnclhvitmynrikkdpkklfvprtviiggkaapgyhmakmiiklitsvad
vvnndpmvgsklkviflenyrvslaekvipatdlseqistagteasgtgnmkfmlngalt
igtmdganvemaeeageenlfifgmriddvaaldkkgyeakeyyealpelklvidqidng
ffspkqpdlfkdiinmlfyhdrfkvfadyeayvkcqdkvsqlymnpkawntmvlkniaas
gkfssdrtikeyaqniwnveps